iPTMnet Report for Q08117 (TLE5)
Protein Information
UniProt AC / UniProt ID | Q08117 / TLE5_HUMAN |
Protein Name | TLE family member 5 |
Gene Name | Name: TLE5 Synonyms:AES,GRG,GRG5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q08117 |
PRO Name | TLE family member 5 (human) |
Definition | A TLE family member 5 that is encoded in the genome of human. |
Short Label | hTLE5 |
Category | organism-gene |
Q08117 (TLE5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R7 | Methylation | score1 | PhosphoSitePlus | |||
S9 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S11 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S12 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
C47 | Methylation | score1 | IEDB | 31844290 | ||
K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
S55 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
Y69 | Phosphorylation | score1 | PhosphoSitePlus | |||
K83 | Ubiquitination | score1 | PhosphoSitePlus | |||
K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
S121 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
S133 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
T143 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
T143 | Phosphorylation | score1 | PhosphoSitePlus | |||
S153 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
S158 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
T161 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
T161 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
S171 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
S176 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
T187 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
S196 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S9 | Phosphorylation | score0 | HPRD | 20068231 | ||
S11 | Phosphorylation | score0 | HPRD | 20068231 | ||
S196 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
S263 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | Q08117 (TLE5) | S121 | Q13309 (SKP2) | unknown | eFIP | 33754069 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T187 | S187 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |