iPTMnet Report for Q08117 (TLE5)
Protein Information
| UniProt AC / UniProt ID | Q08117 / TLE5_HUMAN |
| Protein Name | TLE family member 5 |
| Gene Name | Name: TLE5 Synonyms:AES,GRG,GRG5; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q08117 |
| PRO Name | TLE family member 5 (human) |
| Definition | A TLE family member 5 that is encoded in the genome of human. |
| Short Label | hTLE5 |
| Category | organism-gene |
DAG ViewQ08117 (TLE5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| R7 | Methylation | score1 | PhosphoSitePlus | |||
| S9 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S11 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S12 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
| K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C47 | Methylation | score1 | IEDB | 31844290 | ||
| K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S55 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
| Y69 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K83 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S121 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
| S133 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
| T143 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
| T143 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S153 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
| S158 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
| T161 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
| T161 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
| S171 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
| S176 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928 | ||
| T187 | Phosphorylation | score0 | RLIMS-P | 33754069 | ||
| S196 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S9 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S11 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S196 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S263 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q08117 (TLE5) | S121 | Q13309 (SKP2) | unknown | eFIP | 33754069 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T187 | S187 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |
