iPTMnet Report for Q06265 (EXOSC9)
Protein Information
UniProt AC / UniProt ID | Q06265 / EXOS9_HUMAN |
Protein Name | Exosome complex component RRP45 |
Gene Name | Name: EXOSC9 Synonyms:PMSCL1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q06265 |
PRO Name | exosome complex component RRP45 (human) |
Definition | An exosome complex component RRP45 that is encoded in the genome of human. |
Short Label | hEXOSC9 |
Category | organism-gene |
Q06265 (EXOSC9) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K2 | Ubiquitination | score1 | PhosphoSitePlus | |||
T4 | Phosphorylation | score1 | PhosphoSitePlus | |||
K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
S65 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
K101 | Acetylation | score1 | PhosphoSitePlus | |||
K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
S186 | Phosphorylation | score1 | PhosphoSitePlus | |||
C193 | Methylation | score1 | IEDB | 31844290 | ||
C250 | Methylation | score1 | IEDB | 31844290 | ||
K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
K274 | Ubiquitination | score1 | PhosphoSitePlus | |||
K281 | Acetylation | score1 | PhosphoSitePlus | |||
K281 | Ubiquitination | score1 | PhosphoSitePlus | |||
K297 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K297 | Sumoylation | score1 | PhosphoSitePlus | |||
K297 | Ubiquitination | score1 | PhosphoSitePlus | |||
K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
T305 | Phosphorylation | score1 | PhosphoSitePlus | |||
S306 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 17081983, ... | ||
V325 | Phosphorylation | score1 | UniProt | 24275569 | ||
S327 | Phosphorylation | score1 | UniProt | 24275569 | ||
S346 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
S380 | Phosphorylation | score1 | PhosphoSitePlus | |||
S392 | Phosphorylation | P68400 (CSNK2A1) | score4 | phospho.ELM PhosphoSitePlus Signor UniProt | 18669648, 19217413, 20068231 | |
S394 | Phosphorylation | P68400 (CSNK2A1) | score4 | phospho.ELM PhosphoSitePlus Signor UniProt | 18669648, 19217413, 20068231 | |
K409 | Phosphorylation | score1 | UniProt | 24275569 | ||
I411 | Phosphorylation | score1 | UniProt | 24275569 | ||
T413 | Phosphorylation | score1 | PhosphoSitePlus | |||
K419 | Acetylation | score1 | PhosphoSitePlus | |||
K419 | Sumoylation | score1 | PhosphoSitePlus | |||
S425 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T305 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
S306 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 18767875, ... | ||
S392 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231, ... | ||
S394 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231, ... |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T305 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
S306 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 18767875, ... | ||
S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
S411 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S186 | N186 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K252 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
K274 | N274 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K300 | N300 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S392 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
S392 | L392 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S409 | L409 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S409 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
I411 | T411 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |