iPTMnet Report for Q04912 (MST1R)
Protein Information
| UniProt AC / UniProt ID | Q04912 / RON_HUMAN |
| Protein Name | Macrophage-stimulating protein receptor precursor |
| Gene Name | Name: MST1R Synonyms:PTK8,RON; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q04912 |
| PRO Name | macrophage-stimulating protein receptor (human) |
| Definition | A macrophage-stimulating protein receptor that is encoded in the genome of human. |
| Short Label | hMST1R |
| Category | organism-gene |
DAG ViewQ04912 (MST1R) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S226 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S236 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N488 | N-Glycosylation | score3 | GlyGen UniProt | 22848655 | ||
| Y1012 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1017 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1056 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1071 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1101 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1181 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1198 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 24739671 | ||
| K1223 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1238 | Phosphorylation | Q04912 (MST1R) , K9JYP4 (RON) , P08581 (MET) | score4 | neXtProt phospho.ELM PhosphoSitePlus UniProt | 9045873, 20726546, 10871856, ... | |
| Y1239 | Phosphorylation | P08581 (MET) , K9JYP4 (RON) , Q04912 (MST1R) | score4 | neXtProt phospho.ELM PhosphoSitePlus UniProt | 9045873, 15632155, 10871856 | |
| S1240 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1317 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1353 | Phosphorylation | Q04912 (MST1R) , P08581 (MET) , K9JYP4 (RON) | score4 | neXtProt phospho.ELM PhosphoSitePlus UniProt | 9045873, 10871856, 15632155 | |
| Y1360 | Phosphorylation | P08581 (MET) , K9JYP4 (RON) , Q04912 (MST1R) | score4 | neXtProt phospho.ELM PhosphoSitePlus UniProt | 9045873, 15632155, 10871856 | |
| S1394 | Phosphorylation | P31749 (AKT1) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor | 14505491, 12919677 |
Q04912 (MST1R) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| P08581 (MET) | Y1234 | score3 | neXtProt PhosphoSitePlus | 10871856 | |
| P08581 (MET) | Y1235 | score2 | PhosphoSitePlus | 10871856 | |
| P08581 (MET) | Y1349 | score2 | PhosphoSitePlus | 10871856 | |
| P08581 (MET) | Y1356 | score2 | PhosphoSitePlus | 10871856 | |
| Q04912 (MST1R) | Y1238 | score4 | HPRD neXtProt UniProt | 9045873, 10871856, 15632155 | |
| Q04912 (MST1R) | Y1239 | score4 | HPRD neXtProt UniProt | 9045873, 10871856, 15632155 | |
| Q04912 (MST1R) | Y1353 | score4 | HPRD neXtProt UniProt | 9045873, 10871856, 15632155 | |
| Q04912 (MST1R) | Y1360 | score4 | HPRD neXtProt UniProt | 9045873, 10871856, 15632155 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S1056 | F1056 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K1071 | R1071 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| Y1238 | H1238 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y1238 | C1238 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y1353 | H1353 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| Y1353 | * | Biomuta | DOID:1319 / brain cancer [ cosmic ] |
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