iPTMnet Report for Q04912 (MST1R)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q04912 / RON_HUMAN
Protein Name Macrophage-stimulating protein receptor precursor
Gene Name Name: MST1R
Synonyms:PTK8,RON;
Organism Homo sapiens (Human)

PRO ID PR:Q04912
DAG View
PRO Name macrophage-stimulating protein receptor (human)
Definition A macrophage-stimulating protein receptor that is encoded in the genome of human.
Short Label hMST1R
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q04912 (MST1R) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S215 Phosphorylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
N488 N-Glycosylation GlyGen   UniProt 22848655
Y1012 Phosphorylation PhosphoSitePlus
Y1017 Phosphorylation PhosphoSitePlus
S1056 Phosphorylation PhosphoSitePlus
K1071 Ubiquitination PhosphoSitePlus
Y1101 Phosphorylation PhosphoSitePlus
T1181 Phosphorylation PhosphoSitePlus
Y1198 Phosphorylation PhosphoSitePlus   RLIMS-P 24739671
K1223 Ubiquitination PhosphoSitePlus
Y1238 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 9045873, 20726546, 10871856, ...15632155
Y1238 Phosphorylation K9JYP4 (RON) phospho.ELM 10871856
Y1238 Phosphorylation P08581 (MET) PhosphoSitePlus 10871856
Y1238 Phosphorylation Q04912 (MST1R) neXtProt   UniProt 9045873, 15632155
Y1239 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 9045873, 15632155, 10871856
Y1239 Phosphorylation K9JYP4 (RON) phospho.ELM 10871856
Y1239 Phosphorylation P08581 (MET) PhosphoSitePlus 10871856
Y1239 Phosphorylation Q04912 (MST1R) neXtProt   UniProt 9045873, 15632155
S1240 Phosphorylation PhosphoSitePlus
Y1317 Phosphorylation PhosphoSitePlus
Y1353 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 9045873, 10871856, 15632155
Y1353 Phosphorylation K9JYP4 (RON) phospho.ELM 10871856
Y1353 Phosphorylation P08581 (MET) PhosphoSitePlus 10871856
Y1353 Phosphorylation Q04912 (MST1R) neXtProt   UniProt 9045873, 15632155
Y1360 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 9045873, 15632155, 10871856
Y1360 Phosphorylation K9JYP4 (RON) phospho.ELM 10871856
Y1360 Phosphorylation P08581 (MET) PhosphoSitePlus 10871856
Y1360 Phosphorylation Q04912 (MST1R) neXtProt   UniProt 9045873, 15632155
S1394 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 14505491, 12919677
S1394 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus   Signor 14505491, 12919677
Site PTM Type PTM Enzyme Score Source PMID
Y1238 Phosphorylation HPRD 10871856
Y1238 Phosphorylation Q04912 (MST1R) HPRD 10871856
Y1239 Phosphorylation HPRD 10871856
Y1239 Phosphorylation Q04912 (MST1R) HPRD 10871856
Y1353 Phosphorylation HPRD 10871856
Y1353 Phosphorylation Q04912 (MST1R) HPRD 10871856
Y1360 Phosphorylation HPRD 10871856
Y1360 Phosphorylation Q04912 (MST1R) HPRD 10871856


Q04912 (MST1R) as PTM Enzyme



Substrate Site Score Source PMID
P08581 (MET) Y1234 neXtProt   PhosphoSitePlus 10871856
P08581 (MET) Y1235 PhosphoSitePlus 10871856
P08581 (MET) Y1349 PhosphoSitePlus 10871856
P08581 (MET) Y1356 PhosphoSitePlus 10871856
Q04912 (MST1R) Y1238 HPRD   neXtProt   UniProt 9045873, 10871856, 15632155
Q04912 (MST1R) Y1239 HPRD   neXtProt   UniProt 9045873, 10871856, 15632155
Q04912 (MST1R) Y1353 HPRD   neXtProt   UniProt 9045873, 10871856, 15632155
Q04912 (MST1R) Y1360 HPRD   neXtProt   UniProt 9045873, 10871856, 15632155


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S1056 F1056 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1071 R1071 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y1238 H1238 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1238 C1238 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1353 H1353 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y1353 * Biomuta DOID:1319 / brain cancer [ cosmic ]