iPTMnet Report for Q04446 (GBE1)
Protein Information
UniProt AC / UniProt ID | Q04446 / GLGB_HUMAN |
Protein Name | 1,4-alpha-glucan-branching enzyme |
Gene Name | Name: GBE1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q04446 |
PRO Name | 1,4-alpha-glucan-branching enzyme (human) |
Definition | A 1,4-alpha-glucan-branching enzyme that is encoded in the genome of human. |
Short Label | hGBE1 |
Category | organism-gene |
Q04446 (GBE1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22223895 | ||
T6 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y14 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y37 | Phosphorylation | score1 | PhosphoSitePlus | |||
K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y41 | Phosphorylation | score1 | PhosphoSitePlus | |||
K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
K68 | Acetylation | score1 | PhosphoSitePlus | |||
K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y73 | Phosphorylation | score1 | PhosphoSitePlus | |||
C81 | S-Nitrosylation | score0 | dbSNO | 2212679 | ||
Y87 | Phosphorylation | score1 | PhosphoSitePlus | |||
C88 | S-Nitrosylation | score0 | dbSNO | 2212679, 22126794 | ||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
K162 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y173 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 15592455 | ||
K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y200 | Phosphorylation | score1 | PhosphoSitePlus | |||
S202 | Phosphorylation | score1 | PhosphoSitePlus | |||
K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
C221 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y469 | Phosphorylation | score1 | PhosphoSitePlus | |||
K472 | Ubiquitination | score1 | PhosphoSitePlus | |||
C473 | Methylation | score1 | IEDB | 31844290 | ||
Y476 | Phosphorylation | score1 | PhosphoSitePlus | |||
K554 | Ubiquitination | score1 | PhosphoSitePlus | |||
S559 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y560 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y562 | Phosphorylation | score1 | PhosphoSitePlus | |||
K578 | Ubiquitination | score1 | PhosphoSitePlus | |||
K645 | Ubiquitination | score1 | PhosphoSitePlus | |||
K647 | Ubiquitination | score1 | PhosphoSitePlus | |||
S652 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y657 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | V2 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
Y41 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K68 | T68 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
Y87 | F87 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K132 | T132 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S133 | F133 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K187 | N187 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S202 | C202 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K442 | E442 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
Y469 | C469 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
C473 | R473 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K578 | N578 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S652 | L652 | Biomuta | DOID:263 / kidney cancer [ cosmic ] |