Protein Information

Cytoscape View


UniProt AC / UniProt ID Q04446 / GLGB_HUMAN
Protein Name 1,4-alpha-glucan-branching enzyme
Gene Name Name: GBE1
Organism Homo sapiens (Human)

PRO ID PR:Q04446
DAG View
PRO Name 1,4-alpha-glucan-branching enzyme (human)
Definition A 1,4-alpha-glucan-branching enzyme that is encoded in the genome of human.
Short Label hGBE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q04446 (GBE1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22223895
T6 Phosphorylation PhosphoSitePlus
Y14 Phosphorylation PhosphoSitePlus
Y37 Phosphorylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K68 Acetylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
C81 S-Nitrosylation dbSNO 2212679
Y87 Phosphorylation PhosphoSitePlus
C88 S-Nitrosylation dbSNO 2212679, 22126794
K121 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
Y173 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 15592455
K187 Ubiquitination PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
C221 S-Nitrosylation dbSNO 26338901
K442 Ubiquitination PhosphoSitePlus
Y469 Phosphorylation PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
Y476 Phosphorylation PhosphoSitePlus
K554 Ubiquitination PhosphoSitePlus
S559 Phosphorylation PhosphoSitePlus
Y560 Phosphorylation PhosphoSitePlus
Y562 Phosphorylation PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
K645 Ubiquitination PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
Y657 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y41 * Biomuta DOID:1612 / breast cancer [ tcga ]
K68 T68 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
Y87 * Biomuta DOID:3571 / liver cancer [ icgc ]
K187 N187 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S202 C202 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K442 E442 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]