iPTMnet Report for Q02548 (PAX5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02548 / PAX5_HUMAN
Protein Name Paired box protein Pax-5
Gene Name Name: PAX5
Organism Homo sapiens (Human)

PRO ID PR:Q02548
DAG View
PRO Name paired box protein Pax-5 (human)
Definition A paired box protein PAX-5 that is encoded in the genome of human.
Short Label hPAX5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02548 (PAX5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus
T15 Phosphorylation PhosphoSitePlus
Y102 Phosphorylation PhosphoSitePlus   RLIMS-P 36064939
S133 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S189 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) Signor 22593617
S206 Phosphorylation PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
Y299 Phosphorylation PhosphoSitePlus
R377 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T9 I9 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T9 A9 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T15 K15 Biomuta [ cosmic ]
S133 R133 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S168 F168 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y179 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R377 Q377 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ]
R377 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic ]