iPTMnet Report for Q02548 (PAX5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02548 / PAX5_HUMAN
Protein Name Paired box protein Pax-5
Gene Name Name: PAX5
Organism Homo sapiens (Human)

PRO ID PR:Q02548
DAG View
PRO Name paired box protein Pax-5 (human)
Definition A paired box protein PAX-5 that is encoded in the genome of human.
Short Label hPAX5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02548 (PAX5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus
T15 Phosphorylation PhosphoSitePlus
Y102 Phosphorylation PhosphoSitePlus   RLIMS-P 36064939
S133 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S189 Phosphorylation Signor 22593617
S189 Phosphorylation P27361 (MAPK3) Signor 22593617
S189 Phosphorylation P28482 (MAPK1) Signor 22593617
S206 Phosphorylation PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
Y299 Phosphorylation PhosphoSitePlus
R377 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T9 I9 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T9 A9 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T15 K15 Biomuta [ cosmic ]
S133 R133 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S168 F168 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y179 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R377 Q377 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ]
R377 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic ]