iPTMnet Report for Q01628 (IFITM3)
Protein Information
| UniProt AC / UniProt ID | Q01628 / IFM3_HUMAN |
| Protein Name | Interferon-induced transmembrane protein 3 |
| Gene Name | Name: IFITM3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q01628 |
| PRO Name | interferon-induced transmembrane protein 3 (human) |
| Definition | An interferon-induced transmembrane protein that is a translation product of the IFITM3 gene in human. |
| Short Label | hIFITM3 |
| Category | organism-gene |
DAG ViewQ01628 (IFITM3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| Y20 | Phosphorylation | P06241 (FYN) | score4 | HPRD PhosphoSitePlus RLIMS-P+ RLIMS-P UniProt | 18578522, 26354436, 33149299, ... | |
| K24 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 22511783 | ||
| T42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K83 | Ubiquitination | score2 | UniProt | 22511783 | ||
| K88 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 22511783 | ||
| T94 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y99 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K104 | Ubiquitination | score2 | UniProt | 22511783 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T42 | R42 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| T42 | M42 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:184 / bone cancer [ cosmic ] | |
| K83 | T83 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] |
