iPTMnet Report for Q01628 (IFITM3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01628 / IFM3_HUMAN
Protein Name Interferon-induced transmembrane protein 3
Gene Name Name: IFITM3
Organism Homo sapiens (Human)

PRO ID PR:Q01628
DAG View
PRO Name interferon-induced transmembrane protein 3 (human)
Definition An interferon-induced transmembrane protein that is a translation product of the IFITM3 gene in human.
Short Label hIFITM3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01628 (IFITM3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y20 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P+   RLIMS-P   UniProt 18578522, 26354436, 33149299, ...23055554, 24627473
Y20 Phosphorylation P06241 (FYN) PhosphoSitePlus   RLIMS-P+ 23055554, 24627473
K24 Ubiquitination PhosphoSitePlus   UniProt 22511783
T42 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
K83 Ubiquitination UniProt 22511783
K88 Ubiquitination PhosphoSitePlus   UniProt 22511783
T94 Phosphorylation PhosphoSitePlus
Y99 Phosphorylation PhosphoSitePlus
K104 Ubiquitination UniProt 22511783


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T42 R42 Biomuta DOID:1319 / brain cancer [ cosmic ]
T42 M42 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:184 / bone cancer [ cosmic ]
K83 T83 Biomuta DOID:5041 / esophageal cancer [ cosmic ]