Protein Information

Cytoscape View


UniProt AC / UniProt ID P97377 / CDK2_MOUSE
Protein Name Cyclin-dependent kinase 2
Gene Name Name: Cdk2
Synonyms:Cdkn2;
Organism Mus musculus (Mouse)

PRO ID PR:P97377
DAG View
PRO Name cyclin-dependent kinase 2 (mouse)
Definition A cyclin-dependent kinase 2 that is encoded in the genome of mouse.
Short Label mCDK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P97377 (Cdk2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation PhosphoSitePlus   RLIMS-P 8475101
Y15 Phosphorylation P47810 (Wee1) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 11585773, 26714930, 8475101, ...11509654, 22761665, 25428911
Y19 Phosphorylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
T160 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 24797635, 24886500, 27449088, ...26148348, 26714930, 23028939, 11509654, 21372285, 18382684, 10903150
S218 Phosphorylation UniProt 21183079
Site PTM Type PTM Enzyme Score Source PMID
K33 Acetylation PR:000012332 (KAT2B) PRO 19773423


P97377 (Cdk2) as PTM Enzyme



Substrate Site Score Source PMID
O89090 (Sp1) S61 Signor 11598016
P10085 (Myod1) S200 phospho.ELM   PhosphoSitePlus 10942602, 10082583
P23804 (Mdm2) T216 phospho.ELM   PhosphoSitePlus 11359766
P25976 (Ubtf) S389 phospho.ELM   PhosphoSitePlus   Signor 11698641
P25976 (Ubtf) S484 PhosphoSitePlus 10202152
P28033 (Cebpb) T188 PhosphoSitePlus   UniProt 21183079, 17601773
P46414 (Cdkn1b) T187 UniProt 9399644
P48432 (Sox2) S39 PhosphoSitePlus 26139602
P48432 (Sox2) S253 PhosphoSitePlus 26139602
P48972 (Mybl2) T267 phospho.ELM   PhosphoSitePlus 10593981
P48972 (Mybl2) S283 phospho.ELM   PhosphoSitePlus 10593981
P48972 (Mybl2) S396 phospho.ELM   PhosphoSitePlus 10593981
P48972 (Mybl2) T408 phospho.ELM   PhosphoSitePlus 10593981
P48972 (Mybl2) T443 phospho.ELM 10095772
P48972 (Mybl2) T447 phospho.ELM   PhosphoSitePlus 11264176, 9840932
P48972 (Mybl2) S455 phospho.ELM   PhosphoSitePlus 10593981
P48972 (Mybl2) T490 phospho.ELM   PhosphoSitePlus 11264176, 9840932
P48972 (Mybl2) T497 phospho.ELM   PhosphoSitePlus 11264176, 9840932, 10593981
P48972 (Mybl2) T519 phospho.ELM   PhosphoSitePlus 10593981
P48972 (Mybl2) T522 phospho.ELM   PhosphoSitePlus 10593981
P48972 (Mybl2) T524 phospho.ELM   PhosphoSitePlus 10593981, 10095772
P48972 (Mybl2) S581 phospho.ELM   PhosphoSitePlus 11264176, 9840932, 10593981
P49717 (Mcm4) S3 phospho.ELM 11454864
P49717 (Mcm4) T19 phospho.ELM 11454864, 16519687
P49717 (Mcm4) S53 phospho.ELM 11454864
P54227 (Stmn1) S38 PhosphoSitePlus 19688729
Q03147 (Cdk7) S164 PhosphoSitePlus 7553872
Q60953 (Pml) S528 UniProt 19131326
Q61502 (E2f5) T251 phospho.ELM   PhosphoSitePlus 10783242
Q61937 (Npm1) T232 Signor 11278991
Q6ZWZ2 (Ube2r2) S233 Signor 12037680
Q99JB6 (Foxp3) S19 UniProt 23853094
Q99JB6 (Foxp3) T175 UniProt 23853094
Q9ESJ1 (Cables1) S274 UniProt 11733001
Q9WUU9 (Mcm3ap) S502 phospho.ELM   PhosphoSitePlus 11526238


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P97377 (Cdk2) T160 P46414 (Cdkn1b) unknown eFIP 26148348