iPTMnet Report for P68036 (UBE2L3)
Protein Information
UniProt AC / UniProt ID | P68036 / UB2L3_HUMAN |
Protein Name | Ubiquitin-conjugating enzyme E2 L3 |
Gene Name | Name: UBE2L3 Synonyms:UBCE7,UBCH7; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P68036 |
PRO Name | ubiquitin-conjugating enzyme E2 L3 (human) |
Definition | A ubiquitin-conjugating enzyme E2 L3 that is encoded in the genome of human. |
Short Label | hUBE2L3 |
Category | organism-gene |
P68036 (UBE2L3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K9 | Acetylation | score1 | PhosphoSitePlus | |||
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
K20 | Acetylation | score1 | PhosphoSitePlus | |||
K20 | Ubiquitination | score1 | PhosphoSitePlus | |||
K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
K71 | Ubiquitination | score1 | PhosphoSitePlus | |||
K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
K82 | Acetylation | score1 | PhosphoSitePlus | |||
K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
C86 | S-Nitrosylation | score0 | dbSNO | 19483679, 22178444 | ||
K96 | Acetylation | score1 | PhosphoSitePlus | |||
K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y129 | Phosphorylation | score1 | PhosphoSitePlus | |||
K131 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
K138 | Acetylation | score1 | PhosphoSitePlus | |||
K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
K145 | Acetylation | score1 | PhosphoSitePlus | |||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y147 | Phosphorylation | score1 | PhosphoSitePlus | |||
K150 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K48 | T48 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K48 | M48 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K67 | T67 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K145 | N145 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |