Protein Information

Cytoscape View

UniProt AC / UniProt ID P63279 / UBC9_HUMAN
Protein Name SUMO-conjugating enzyme UBC9
Gene Name Name: UBE2I
Organism Homo sapiens (Human)

PRO ID PR:P63279
DAG View
PRO Name SUMO-conjugating enzyme UBC9 (human)
Definition A SUMO-conjugating enzyme UBC9 that is encoded in the genome of human.
Short Label hUBE2I
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P63279 (UBE2I) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378
S2 Phosphorylation HPRD   PhosphoSitePlus 20058876
K14 Sumoylation PhosphoSitePlus
K18 Sumoylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus
K48 Sumoylation PhosphoSitePlus
K49 Sumoylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K65 Acetylation PhosphoSitePlus   UniProt 19608861
K65 Sumoylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus   RLIMS-P 22509284
S71 Phosphorylation P06493 (CDK1) neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 24953629, 23186163, 22407595, ...22509284
K74 Ubiquitination PhosphoSitePlus
K101 Sumoylation PhosphoSitePlus
K146 Sumoylation PhosphoSitePlus
K153 Sumoylation PhosphoSitePlus
K154 Sumoylation PhosphoSitePlus

Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:P29590-4 (hPML/iso:4) Interaction PR:P63279 (hUBE2I) PRO 9885291

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K49 E49 Biomuta DOID:1115 / sarcoma [ tcga ]