iPTMnet Report for P63241 (EIF5A)
Protein Information
| UniProt AC / UniProt ID | P63241 / IF5A1_HUMAN |
| Protein Name | Eukaryotic translation initiation factor 5A-1 |
| Gene Name | Name: EIF5A |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P63241 |
| PRO Name | eukaryotic translation initiation factor 5A-1 (human) |
| Definition | A eukaryotic translation initiation factor 5A-1 that is encoded in the genome of human. |
| Short Label | hEIF5A |
| Category | organism-gene |
P63241 (EIF5A) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K27 | Acetylation | score1 | PhosphoSitePlus | |||
| K27 | Sumoylation | score1 | PhosphoSitePlus | |||
| K27 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K34 | Acetylation | score1 | PhosphoSitePlus | |||
| K34 | Sumoylation | score1 | PhosphoSitePlus | |||
| K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C38 | Methylation | score1 | IEDB | 31844290 | ||
| K39 | Acetylation | score1 | PhosphoSitePlus | |||
| K39 | Sumoylation | score1 | PhosphoSitePlus | |||
| K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S46 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K47 | Acetylation | score3 | PhosphoSitePlus UniProt | 19379712 | ||
| K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K55 | Acetylation | score1 | PhosphoSitePlus | |||
| T65 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K67 | Acetylation | score1 | PhosphoSitePlus | |||
| K67 | Sumoylation | score1 | PhosphoSitePlus | |||
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K68 | Acetylation | score1 | PhosphoSitePlus | |||
| K68 | Methylation | score1 | PhosphoSitePlus | |||
| K68 | Sumoylation | score1 | PhosphoSitePlus | |||
| K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y69 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C73 | Methylation | score1 | IEDB | 31844290 | ||
| K85 | Acetylation | score1 | PhosphoSitePlus | |||
| K85 | Sumoylation | score1 | PhosphoSitePlus | |||
| K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S100 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S105 | O-Glycosylation | score1 | GlyGen | 23301498, 16408927, 35138101, ... | ||
| R113 | Methylation | score1 | PhosphoSitePlus | |||
| K121 | Acetylation | score1 | PhosphoSitePlus | |||
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K126 | Sumoylation | score1 | PhosphoSitePlus | |||
| K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K150 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S15 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S23 | L23 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| K27 | N27 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] | |
| K27 | T27 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S46 | L46 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y69 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| Y98 | H98 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S100 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| R113 | H113 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| R113 | C113 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K126 | T126 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| Y127 | C127 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| K150 | E150 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View