iPTMnet Report for P63241 (EIF5A)
Protein Information
UniProt AC / UniProt ID | P63241 / IF5A1_HUMAN |
Protein Name | Eukaryotic translation initiation factor 5A-1 |
Gene Name | Name: EIF5A |
Organism | Homo sapiens (Human) |
PRO ID | PR:P63241 |
PRO Name | eukaryotic translation initiation factor 5A-1 (human) |
Definition | A eukaryotic translation initiation factor 5A-1 that is encoded in the genome of human. |
Short Label | hEIF5A |
Category | organism-gene |
P63241 (EIF5A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T9 | Phosphorylation | score1 | PhosphoSitePlus | |||
S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
T17 | Phosphorylation | score1 | PhosphoSitePlus | |||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
K27 | Acetylation | score1 | PhosphoSitePlus | |||
K27 | Sumoylation | score1 | PhosphoSitePlus | |||
K27 | Ubiquitination | score1 | PhosphoSitePlus | |||
K34 | Acetylation | score1 | PhosphoSitePlus | |||
K34 | Sumoylation | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
C38 | Methylation | score1 | IEDB | 31844290 | ||
K39 | Acetylation | score1 | PhosphoSitePlus | |||
K39 | Sumoylation | score1 | PhosphoSitePlus | |||
K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
S46 | Phosphorylation | score1 | PhosphoSitePlus | |||
K47 | Acetylation | score3 | PhosphoSitePlus UniProt | 19379712 | ||
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
K55 | Acetylation | score1 | PhosphoSitePlus | |||
T65 | Phosphorylation | score1 | PhosphoSitePlus | |||
K67 | Acetylation | score1 | PhosphoSitePlus | |||
K67 | Sumoylation | score1 | PhosphoSitePlus | |||
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
K68 | Acetylation | score1 | PhosphoSitePlus | |||
K68 | Methylation | score1 | PhosphoSitePlus | |||
K68 | Sumoylation | score1 | PhosphoSitePlus | |||
K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y69 | Phosphorylation | score1 | PhosphoSitePlus | |||
C73 | Methylation | score1 | IEDB | 31844290 | ||
K85 | Acetylation | score1 | PhosphoSitePlus | |||
K85 | Sumoylation | score1 | PhosphoSitePlus | |||
K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y98 | Phosphorylation | score1 | PhosphoSitePlus | |||
S100 | Phosphorylation | score1 | PhosphoSitePlus | |||
S105 | O-Glycosylation | score1 | GlyGen | 23301498, 16408927, 35138101, ... | ||
R113 | Methylation | score1 | PhosphoSitePlus | |||
K121 | Acetylation | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
K126 | Sumoylation | score1 | PhosphoSitePlus | |||
K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y127 | Phosphorylation | score1 | PhosphoSitePlus | |||
K150 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S15 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S23 | L23 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
K27 | N27 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] | |
K27 | T27 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S46 | L46 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
Y69 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
Y98 | H98 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S100 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
R113 | H113 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
R113 | C113 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K126 | T126 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y127 | C127 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K150 | E150 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |