iPTMnet Report for P57682 (KLF3)
Protein Information
| UniProt AC / UniProt ID | P57682 / KLF3_HUMAN |
| Protein Name | Krueppel-like factor 3 |
| Gene Name | Name: KLF3 Synonyms:BKLF; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P57682 |
| PRO Name | krueppel-like factor 3 (human) |
| Definition | A krueppel-like factor 3 that is encoded in the genome of human. |
| Short Label | hKLF3 |
| Category | organism-gene |
DAG ViewP57682 (KLF3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K10 | Sumoylation | score1 | PhosphoSitePlus | |||
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y38 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S71 | Phosphorylation | Q9H2X6 (HIPK2) | score4 | PhosphoSitePlus UniProt | 23186163, 25659434 | |
| S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S78 | Phosphorylation | Q9H2X6 (HIPK2) | score2 | PhosphoSitePlus | 25659434 | |
| S92 | Phosphorylation | Q9H2X6 (HIPK2) | score4 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 25659434, ... | |
| S96 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S99 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S100 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S101 | Phosphorylation | Q9H2X6 (HIPK2) | score4 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 25659434 | |
| Y107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S108 | Phosphorylation | Q9H2X6 (HIPK2) | score2 | PhosphoSitePlus | 25659434 | |
| S111 | Phosphorylation | Q9H2X6 (HIPK2) | score4 | PhosphoSitePlus UniProt | 25659434, 20068231 | |
| S132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K198 | Sumoylation | score1 | PhosphoSitePlus | |||
| S216 | Phosphorylation | Q9H2X6 (HIPK2) | score2 | PhosphoSitePlus | 25659434 | |
| S222 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S224 | Phosphorylation | Q9H2X6 (HIPK2) | score2 | PhosphoSitePlus | 25659434 | |
| S250 | Phosphorylation | Q9H2X6 (HIPK2) | score4 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983, 25659434 | |
| T253 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T285 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K288 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S18 | Phosphorylation | score0 | HPRD | 19413330 | ||
| S92 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
| S96 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S99 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S101 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
| Y107 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S108 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S111 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S216 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S224 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S250 | Phosphorylation | score0 | HPRD | 19651622, 17081983, 18452278 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T49 | I49 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T49 | A49 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S74 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S78 | L78 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| S99 | C99 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S100 | F100 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S216 | P216 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S224 | F224 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
