iPTMnet Report for P57682 (KLF3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P57682 / KLF3_HUMAN
Protein Name Krueppel-like factor 3
Gene Name Name: KLF3
Synonyms:BKLF;
Organism Homo sapiens (Human)

PRO ID PR:P57682
DAG View
PRO Name krueppel-like factor 3 (human)
Definition A krueppel-like factor 3 that is encoded in the genome of human.
Short Label hKLF3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P57682 (KLF3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Sumoylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
Y21 Phosphorylation PhosphoSitePlus
Y38 Phosphorylation PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus   UniProt 23186163, 25659434
S71 Phosphorylation Q9H2X6 (HIPK2) PhosphoSitePlus 25659434
S74 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus 25659434
S78 Phosphorylation Q9H2X6 (HIPK2) PhosphoSitePlus 25659434
S92 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 25659434, ...20068231
S92 Phosphorylation Q9H2X6 (HIPK2) PhosphoSitePlus 25659434
S96 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S101 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 25659434
S101 Phosphorylation Q9H2X6 (HIPK2) PhosphoSitePlus 25659434
Y107 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus 25659434
S108 Phosphorylation Q9H2X6 (HIPK2) PhosphoSitePlus 25659434
S111 Phosphorylation PhosphoSitePlus   UniProt 25659434, 20068231
S111 Phosphorylation Q9H2X6 (HIPK2) PhosphoSitePlus 25659434
S132 Phosphorylation PhosphoSitePlus
K198 Sumoylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus 25659434
S216 Phosphorylation Q9H2X6 (HIPK2) PhosphoSitePlus 25659434
S222 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus 25659434
S224 Phosphorylation Q9H2X6 (HIPK2) PhosphoSitePlus 25659434
S250 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 25659434
S250 Phosphorylation Q9H2X6 (HIPK2) PhosphoSitePlus 25659434
T253 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
T285 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation HPRD 19413330
S92 Phosphorylation HPRD 19651622, 18669648, 20068231
S96 Phosphorylation HPRD 20068231
S99 Phosphorylation HPRD 20068231
S101 Phosphorylation HPRD 19651622, 18669648, 20068231
Y107 Phosphorylation HPRD 20068231
S108 Phosphorylation HPRD 20068231
S111 Phosphorylation HPRD 20068231
S216 Phosphorylation HPRD 18452278
S224 Phosphorylation HPRD 18452278
S250 Phosphorylation HPRD 19651622, 17081983, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T49 I49 Biomuta DOID:4159 / skin cancer [ cosmic ]
T49 A49 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S74 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S78 L78 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S99 C99 Biomuta DOID:1324 / lung cancer [ cosmic ]
S100 F100 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S216 P216 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S224 F224 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]