iPTMnet Report for P56747 (CLDN6)
Protein Information
UniProt AC / UniProt ID | P56747 / CLD6_HUMAN |
Protein Name | Claudin-6 |
Gene Name | Name: CLDN6 ORFNames:UNQ757/PRO1488; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P56747 |
PRO Name | claudin-6 (human) |
Definition | A claudin-6 that is encoded in the genome of human. |
Short Label | hCLDN6 |
Category | organism-gene |
P56747 (CLDN6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y196 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y200 | Phosphorylation | score1 | PhosphoSitePlus | |||
S201 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
S201 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 21406692, 19664995 | ||
T202 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
T202 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19664995 | ||
S203 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
S203 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 21406692, 19664995 | ||
S208 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
S208 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S212 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
Y214 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18083107 | ||
T216 | Phosphorylation | score1 | PhosphoSitePlus | |||
K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y219 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18083107 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y196 | C196 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S201 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S203 | T203 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S212 | F212 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K217 | N217 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] |