iPTMnet Report for P55210 (CASP7)
Protein Information
UniProt AC / UniProt ID | P55210 / CASP7_HUMAN |
Protein Name | Caspase-7 precursor |
Gene Name | Name: CASP7 Synonyms:MCH3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P55210 |
PRO Name | caspase-7 (human) |
Definition | A caspase-7 that is encoded in the genome of human. |
Short Label | hCASP7 |
Category | organism-gene |
P55210 (CASP7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22223895 | ||
S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
S30 | Phosphorylation | score4 | neXtProt PhosphoSitePlus RLIMS-P Signor UniProt | 21555521, 27889207 | ||
S30 | Phosphorylation | Q13177 (PAK2) | score3 | neXtProt PhosphoSitePlus Signor | 21555521 | |
S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
S37 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K38 | Methylation | score1 | PhosphoSitePlus | |||
K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
T44 | Phosphorylation | score1 | PhosphoSitePlus | |||
S47 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y58 | Phosphorylation | score0 | RLIMS-P | 24407236 | ||
K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
K99 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y151 | Phosphorylation | score0 | RLIMS-P | 24407236 | ||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
K172 | Ubiquitination | score1 | PhosphoSitePlus | |||
T173 | Phosphorylation | score4 | neXtProt PhosphoSitePlus RLIMS-P Signor UniProt | 21555521, 27889207 | ||
T173 | Phosphorylation | Q13177 (PAK2) | score3 | neXtProt PhosphoSitePlus Signor | 21555521 | |
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y229 | Phosphorylation | score0 | RLIMS-P | 24407236 | ||
Y230 | Phosphorylation | score0 | RLIMS-P | 24407236 | ||
S234 | Phosphorylation | score1 | PhosphoSitePlus | |||
S239 | Phosphorylation | score4 | neXtProt PhosphoSitePlus RLIMS-P Signor UniProt | 21555521, 27889207 | ||
S239 | Phosphorylation | Q13177 (PAK2) | score3 | neXtProt PhosphoSitePlus Signor | 21555521 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S16 | Phosphorylation | score0 | HPRD | 19413330 | ||
T193 | Phosphorylation | score1 | PhosphoSitePlus | |||
T200 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S30 | L30 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K160 | R160 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K160 | E160 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
Y230 | S230 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S234 | R234 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S234 | N234 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |