iPTMnet Report for P55210 (CASP7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55210 / CASP7_HUMAN
Protein Name Caspase-7 precursor
Gene Name Name: CASP7
Synonyms:MCH3;
Organism Homo sapiens (Human)

PRO ID PR:P55210
DAG View
PRO Name caspase-7 (human)
Definition A caspase-7 that is encoded in the genome of human.
Short Label hCASP7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55210 (CASP7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895
S16 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
S30 Phosphorylation Q13177 (PAK2) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21555521, 27889207
S34 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus   UniProt 23186163
K38 Methylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
T44 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
Y58 Phosphorylation RLIMS-P 24407236
K69 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
Y151 Phosphorylation RLIMS-P 24407236
K153 Ubiquitination PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
T173 Phosphorylation Q13177 (PAK2) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21555521, 27889207
K177 Ubiquitination PhosphoSitePlus
Y229 Phosphorylation RLIMS-P 24407236
Y230 Phosphorylation RLIMS-P 24407236
S234 Phosphorylation PhosphoSitePlus
S239 Phosphorylation Q13177 (PAK2) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21555521, 27889207
Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation HPRD 19413330
T193 Phosphorylation PhosphoSitePlus
T200 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S30 L30 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K160 R160 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K160 E160 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y230 S230 Biomuta DOID:1324 / lung cancer [ cosmic ]
S234 R234 Biomuta DOID:1324 / lung cancer [ cosmic ]
S234 N234 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]