iPTMnet Report for P55199 (ELL)
Protein Information
| UniProt AC / UniProt ID | P55199 / ELL_HUMAN |
| Protein Name | RNA polymerase II elongation factor ELL |
| Gene Name | Name: ELL Synonyms:C19orf17; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P55199 |
| PRO Name | RNA polymerase II elongation factor ELL (human) |
| Definition | An RNA polymerase II elongation factor ELL that is encoded in the genome of human. |
| Short Label | hELL |
| Category | organism-gene |
P55199 (ELL) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| K5 | Acetylation | score1 | PhosphoSitePlus | |||
| S9 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K29 | Acetylation | score1 | PhosphoSitePlus | |||
| C110 | Methylation | score1 | IEDB | 31844290 | ||
| T119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T123 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S133 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S145 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T170 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17924679 | ||
| T180 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S194 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S203 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T258 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C259 | Methylation | score1 | IEDB | 31844290 | ||
| T260 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y266 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K285 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S308 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S309 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 23186163, 19664995, 18669648, ... | ||
| S309 | Phosphorylation | P42345 (MTOR) | score1 | PhosphoSitePlus | 21659604 | |
| S317 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S319 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K355 | Acetylation | score1 | PhosphoSitePlus | |||
| S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T431 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S437 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
| S442 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648, 17081983, 20068231 | ||
| S444 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K451 | Methylation | score1 | PhosphoSitePlus | |||
| K456 | Methylation | score1 | PhosphoSitePlus | |||
| K465 | Methylation | score1 | PhosphoSitePlus | |||
| T506 | Phosphorylation | score1 | IEDB | 32357974 | ||
| S519 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S561 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 17525332, 18077418 | ||
| S564 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K583 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S13 | P13 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S18 | I18 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T119 | M119 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K285 | T285 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| S319 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S319 | W319 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| K355 | N355 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S444 | L444 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| K451 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T506 | M506 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S519 | L519 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View