Protein Information

Cytoscape View


UniProt AC / UniProt ID P55199 / ELL_HUMAN
Protein Name RNA polymerase II elongation factor ELL
Gene Name Name: ELL
Synonyms:C19orf17;
Organism Homo sapiens (Human)

PRO ID PR:P55199
DAG View
PRO Name RNA polymerase II elongation factor ELL (human)
Definition An RNA polymerase II elongation factor ELL that is encoded in the genome of human.
Short Label hELL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55199 (ELL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S9 Phosphorylation HPRD 20068231
Y10 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
T119 Phosphorylation PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S133 Phosphorylation HPRD 20068231
S145 Phosphorylation HPRD 20068231
T170 Phosphorylation HPRD   PhosphoSitePlus 17924679
T180 Phosphorylation PhosphoSitePlus   UniProt 23186163
S191 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
S309 Phosphorylation P42345 (MTOR) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 19664995, 18669648, ...21659604, 20068231
S317 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
K355 Acetylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
T431 Phosphorylation PhosphoSitePlus
S437 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S442 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983, 20068231
S444 Phosphorylation PhosphoSitePlus
K451 Methylation PhosphoSitePlus
K456 Methylation PhosphoSitePlus
K465 Methylation PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
S561 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332, 18077418
S564 Phosphorylation PhosphoSitePlus
K583 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 P13 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S18 I18 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T119 M119 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K285 T285 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S319 * Biomuta DOID:4159 / skin cancer [ icgc ]
S319 W319 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K355 N355 Biomuta DOID:1324 / lung cancer [ tcga ]
S444 L444 Biomuta DOID:0070003 / blastoma [ cosmic ]
S519 L519 Biomuta DOID:9256 / colorectal cancer [ tcga ]