iPTMnet Report for P55087 (AQP4)
Protein Information
| UniProt AC / UniProt ID | P55087 / AQP4_HUMAN |
| Protein Name | Aquaporin-4 |
| Gene Name | Name: AQP4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P55087 |
| PRO Name | aquaporin-4 (human) |
| Definition | An aquaporin-4 that is encoded in the genome of human. |
| Short Label | hAQP4 |
| Category | organism-gene |
DAG ViewP55087 (AQP4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S111 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 19850109 | ||
| S180 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P | 19761816, 19850109 | ||
| S180 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 19761816 | |
| S276 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P | 11742978, 32413299, 26013827 | ||
| S276 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 26013827 | |
| Y277 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S285 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11742978 | ||
| T289 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K295 | Methylation | score1 | PhosphoSitePlus | |||
| S316 | Phosphorylation | score2 | phospho.ELM | 11742978 | ||
| S321 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S322 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S276 | Phosphorylation | score1 | HPRD | 11742978 | ||
| S276 | Phosphorylation | P19784 (CSNK2A2) | score1 | HPRD | 11742978 | |
| S276 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 11742978 | |
| S285 | Phosphorylation | score1 | HPRD | 11742978 | ||
| S285 | Phosphorylation | P19784 (CSNK2A2) | score1 | HPRD | 11742978 | |
| S285 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 11742978 | |
| S316 | Phosphorylation | score1 | HPRD | 11742978 | ||
| S316 | Phosphorylation | P19784 (CSNK2A2) | score1 | HPRD | 11742978 | |
| S316 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 11742978 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S254 | Phosphorylation | score1 | HPRD | 11742978 | ||
| S254 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 11742978 | |
| S263 | Phosphorylation | score1 | HPRD | 11742978 | ||
| S263 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 11742978 | |
| S294 | Phosphorylation | score1 | HPRD | 11742978 | ||
| S294 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 11742978 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S263 | I263 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S294 | F294 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
