iPTMnet Report for P54753 (EPHB3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P54753 / EPHB3_HUMAN
Protein Name Ephrin type-B receptor 3 precursor
Gene Name Name: EPHB3
Synonyms:ETK2,HEK2,TYRO6;
Organism Homo sapiens (Human)

PRO ID PR:P54753
DAG View
PRO Name ephrin type-B receptor 3 (human)
Definition An ephrin type-B receptor 3 that is encoded in the genome of human.
Short Label hEPHB3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P54753 (EPHB3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S167 Phosphorylation PhosphoSitePlus
S180 Phosphorylation IEDB 35494241
S201 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
N351 N-Glycosylation GlyGen 29741879
S390 O-Glycosylation GlyGen 29351928
S413 Phosphorylation PhosphoSitePlus
N445 N-Glycosylation GlyGen 23090970, 29741879, 29671580, ...24190977
T448 Phosphorylation PhosphoSitePlus
T458 Phosphorylation PhosphoSitePlus
Y593 Phosphorylation PhosphoSitePlus
T594 Phosphorylation PhosphoSitePlus
Y600 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
Y608 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus 17016520, 15951569, 17389395
T613 Phosphorylation PhosphoSitePlus
Y614 Phosphorylation P54753 (EPHB3) HPRD   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   UniProt 9674711
T666 Phosphorylation PhosphoSitePlus
T731 Phosphorylation PhosphoSitePlus
Y754 Phosphorylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
T791 Phosphorylation PhosphoSitePlus
Y792 Phosphorylation HPRD   PhosphoSitePlus 17016520, 20068231
S794 Phosphorylation PhosphoSitePlus
S795 Phosphorylation PhosphoSitePlus
Y812 Phosphorylation PhosphoSitePlus
T891 Phosphorylation PhosphoSitePlus
S901 Phosphorylation PhosphoSitePlus
Y924 Phosphorylation PhosphoSitePlus
T971 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N445 N-Glycosylation PRO 29671580


P54753 (EPHB3) as PTM Enzyme



Substrate Site Score Source PMID
P32004 (L1CAM) Y1229 neXtProt 22579729
P54753 (EPHB3) Y614 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 9674711


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047307 (hEPHB3/SigPep-/Phos:1) pY608,pY614 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S167 L167 Biomuta DOID:1319 / brain cancer [ cosmic ]
S180 N180 Biomuta DOID:363 / uterine cancer [ icgc ]
T458 A458 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y614 * Biomuta DOID:1612 / breast cancer [ cosmic ]
T666 M666 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S775 L775 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S780 F780 Biomuta DOID:4159 / skin cancer [ cosmic ]
S788 F788 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T791 A791 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S795 F795 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]