iPTMnet Report for P54753 (EPHB3)
Protein Information
| UniProt AC / UniProt ID | P54753 / EPHB3_HUMAN |
| Protein Name | Ephrin type-B receptor 3 precursor |
| Gene Name | Name: EPHB3 Synonyms:ETK2,HEK2,TYRO6; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P54753 |
| PRO Name | ephrin type-B receptor 3 (human) |
| Definition | An ephrin type-B receptor 3 that is encoded in the genome of human. |
| Short Label | hEPHB3 |
| Category | organism-gene |
DAG ViewP54753 (EPHB3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S167 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S180 | Phosphorylation | score1 | IEDB | 35494241 | ||
| S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S204 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S249 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N351 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| S390 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| S413 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N445 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 29671580, ... | ||
| T448 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T458 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y593 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T594 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y600 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18083107 | ||
| Y608 | Phosphorylation | score2 | HPRD phospho.ELM PRO PhosphoSitePlus | 17016520, 15951569, 17389395 | ||
| T613 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y614 | Phosphorylation | score3 | HPRD neXtProt phospho.ELM PRO PhosphoSitePlus UniProt | 9674711 | ||
| Y614 | Phosphorylation | P54753 (EPHB3) | score3 | HPRD neXtProt phospho.ELM PhosphoSitePlus UniProt | 9674711 | |
| T666 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T731 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y754 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S768 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S775 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S780 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S788 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T791 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y792 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17016520, 20068231 | ||
| S794 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S795 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y812 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T891 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S901 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y924 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T971 | Phosphorylation | score1 | PhosphoSitePlus |
P54753 (EPHB3) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| P32004 (L1CAM) | Y1229 | score2 | neXtProt | 22579729 | |
| P54753 (EPHB3) | Y614 | score3 | HPRD neXtProt phospho.ELM PhosphoSitePlus UniProt | 9674711 |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000047307 (hEPHB3/SigPep-/Phos:1) | pY608,pY614 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S167 | L167 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S180 | N180 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T458 | A458 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| Y614 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| T666 | M666 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S775 | L775 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S780 | F780 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S788 | F788 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T791 | A791 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S795 | F795 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
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