iPTMnet Report for P54687 (BCAT1)
Protein Information
| UniProt AC / UniProt ID | P54687 / BCAT1_HUMAN |
| Protein Name | Branched-chain-amino-acid aminotransferase, cytosolic |
| Gene Name | Name: BCAT1 Synonyms:BCT1,ECA39; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P54687 |
| PRO Name | branched-chain-amino-acid aminotransferase, cytosolic (human) |
| Definition | A branched-chain-amino-acid aminotransferase, cytosolic that is encoded in the genome of human. |
| Short Label | hBCAT1 |
| Category | organism-gene |
P54687 (BCAT1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 19413330 | ||
| K2 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R119 | Methylation | score1 | PhosphoSitePlus | |||
| K134 | Acetylation | score1 | PhosphoSitePlus | |||
| K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C140 | Methylation | score1 | IEDB | 31844290 | ||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C235 | Methylation | score1 | IEDB | 31844290 | ||
| K305 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S331 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T333 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C338 | Methylation | score1 | IEDB | 31844290 | ||
| S341 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y345 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K346 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K368 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T370 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T25 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S30 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S17 | N17 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| S17 | R17 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S18 | L18 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K26 | N26 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S30 | L30 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K107 | T107 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R119 | G119 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S341 | F341 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View