iPTMnet Report for P54687 (BCAT1)
Protein Information
UniProt AC / UniProt ID | P54687 / BCAT1_HUMAN |
Protein Name | Branched-chain-amino-acid aminotransferase, cytosolic |
Gene Name | Name: BCAT1 Synonyms:BCT1,ECA39; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P54687 |
PRO Name | branched-chain-amino-acid aminotransferase, cytosolic (human) |
Definition | A branched-chain-amino-acid aminotransferase, cytosolic that is encoded in the genome of human. |
Short Label | hBCAT1 |
Category | organism-gene |
P54687 (BCAT1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
K2 | Ubiquitination | score1 | PhosphoSitePlus | |||
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
T13 | Phosphorylation | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
R119 | Methylation | score1 | PhosphoSitePlus | |||
K134 | Acetylation | score1 | PhosphoSitePlus | |||
K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
C140 | Methylation | score1 | IEDB | 31844290 | ||
K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
C235 | Methylation | score1 | IEDB | 31844290 | ||
K305 | Ubiquitination | score1 | PhosphoSitePlus | |||
S331 | Phosphorylation | score1 | PhosphoSitePlus | |||
T333 | Phosphorylation | score1 | PhosphoSitePlus | |||
C338 | Methylation | score1 | IEDB | 31844290 | ||
S341 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y345 | Phosphorylation | score1 | PhosphoSitePlus | |||
K346 | Ubiquitination | score1 | PhosphoSitePlus | |||
K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
K368 | Ubiquitination | score1 | PhosphoSitePlus | |||
T370 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
T25 | Phosphorylation | score1 | PhosphoSitePlus | |||
S30 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S17 | N17 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
S17 | R17 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S18 | L18 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K26 | N26 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S30 | L30 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K107 | T107 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R119 | G119 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S341 | F341 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |