iPTMnet Report for P54652 (HSPA2)
Protein Information
| UniProt AC / UniProt ID | P54652 / HSP72_HUMAN |
| Protein Name | Heat shock-related 70 kDa protein 2 |
| Gene Name | Name: HSPA2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P54652 |
| PRO Name | heat shock-related 70 kDa protein 2 (human) |
| Definition | A heat shock-related 70 kDa protein 2 that is encoded in the genome of human. |
| Short Label | hHSPA2 |
| Category | organism-gene |
P54652 (HSPA2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N36 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| T38 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S41 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y42 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| T46 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R50 | Methylation | score1 | PhosphoSitePlus | |||
| K57 | Acetylation | score1 | PhosphoSitePlus | |||
| T65 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T67 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K72 | Acetylation | score1 | PhosphoSitePlus | |||
| K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y108 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| K109 | Acetylation | score1 | PhosphoSitePlus | |||
| K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T112 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S121 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S122 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T126 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T159 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T164 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T166 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T178 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K188 | Acetylation | score1 | PhosphoSitePlus | |||
| K188 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T229 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K249 | Acetylation | score1 | PhosphoSitePlus | |||
| T268 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T276 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K322 | Acetylation | score1 | PhosphoSitePlus | |||
| K328 | Acetylation | score1 | PhosphoSitePlus | |||
| K328 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K348 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K351 | Acetylation | score1 | PhosphoSitePlus | |||
| K351 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K360 | Acetylation | score1 | PhosphoSitePlus | |||
| K360 | Sumoylation | score1 | PhosphoSitePlus | |||
| K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K364 | Sumoylation | score1 | PhosphoSitePlus | |||
| K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S365 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T421 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K454 | Acetylation | score1 | PhosphoSitePlus | |||
| K454 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T465 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R472 | Methylation | score1 | PhosphoSitePlus | |||
| T498 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K500 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K503 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T505 | O-Glycosylation | score1 | GlyGen | 16408927, 30397120, 18369606, ... | ||
| T505 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K510 | Acetylation | score1 | PhosphoSitePlus | |||
| K510 | Sumoylation | score1 | PhosphoSitePlus | |||
| K510 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K515 | Acetylation | score1 | PhosphoSitePlus | |||
| R520 | Methylation | score1 | PhosphoSitePlus | |||
| R527 | Methylation | score1 | PhosphoSitePlus | |||
| K564 | Methylation | score1 | PhosphoSitePlus | |||
| T634 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T38 | S38 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| R50 | C50 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T65 | I65 | Biomuta | [ cosmic ] | |
| K101 | R101 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T166 | M166 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ icgc ] | |
| T178 | K178 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
| T178 | M178 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S224 | F224 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T229 | A229 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T268 | A268 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
| T301 | M301 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T421 | A421 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K454 | N454 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| R472 | C472 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| R472 | H472 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View