iPTMnet Report P54652 HSPA2

Protein Information

UniProt AC / UniProt ID	P54652 / HSP72_HUMAN
Protein Name	Heat shock-related 70 kDa protein 2
Gene Name	Name: HSPA2
Organism	Homo sapiens (Human)

PRO ID	PR:P54652 DAG View
PRO Name	heat shock-related 70 kDa protein 2 (human)
Definition	A heat shock-related 70 kDa protein 2 that is encoded in the genome of human.
Short Label	hHSPA2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P54652 (HSPA2) as Substrate

P54652

Expanded View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position Y16 K26 N36 T38 T39 S41 Y42 T46 T48 R50 K57 T65 T67 K72 K78 K101 K103 Y108 K109 T112 K113 S121 S122 T126 T159 T164 T166 T178 Y184 K188 K189 K223 S224 T225 T229 K249 T268 T276 S280 T301 K322 K328 K348 K351 K360 K364 S365 T421 K454 T465 R472 T498 K500 K503 T505 K510 K515 R520 R527 K564 T634	PTM Type Select all Acetylation Methylation N-Glycosylation O-Glycosylation Phosphorylation Sumoylation Ubiquitination	Score Select all 0 1 2	Source Select all GlyGen HPRD PhosphoSitePlus phospho.ELM	PMID
Y16	Phosphorylation	score1	PhosphoSitePlus
K26	Ubiquitination	score1	PhosphoSitePlus
N36	N-Glycosylation	score1	GlyGen	24190977
T38	Phosphorylation	score1	PhosphoSitePlus
T39	Phosphorylation	score1	PhosphoSitePlus
S41	Phosphorylation	score1	PhosphoSitePlus
Y42	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18083107
T46	Phosphorylation	score1	PhosphoSitePlus
T48	Phosphorylation	score1	PhosphoSitePlus
R50	Methylation	score1	PhosphoSitePlus
K57	Acetylation	score1	PhosphoSitePlus
T65	Phosphorylation	score1	PhosphoSitePlus
T67	Phosphorylation	score1	PhosphoSitePlus
K72	Acetylation	score1	PhosphoSitePlus
K78	Ubiquitination	score1	PhosphoSitePlus
K101	Ubiquitination	score1	PhosphoSitePlus
K103	Ubiquitination	score1	PhosphoSitePlus
Y108	Phosphorylation	score2	phospho.ELM PhosphoSitePlus	18083107
K109	Acetylation	score1	PhosphoSitePlus
K109	Ubiquitination	score1	PhosphoSitePlus
T112	Phosphorylation	score1	PhosphoSitePlus
K113	Ubiquitination	score1	PhosphoSitePlus
S121	Phosphorylation	score0	HPRD	20068231
S122	Phosphorylation	score0	HPRD	20068231
T126	Phosphorylation	score1	PhosphoSitePlus
T159	Phosphorylation	score1	PhosphoSitePlus
T164	Phosphorylation	score1	PhosphoSitePlus
T166	Phosphorylation	score1	PhosphoSitePlus
T178	Phosphorylation	score1	PhosphoSitePlus
Y184	Phosphorylation	score1	PhosphoSitePlus
K188	Acetylation	score1	PhosphoSitePlus
K188	Ubiquitination	score1	PhosphoSitePlus
K189	Ubiquitination	score1	PhosphoSitePlus
K223	Ubiquitination	score1	PhosphoSitePlus
S224	Phosphorylation	score1	PhosphoSitePlus
T225	Phosphorylation	score1	PhosphoSitePlus
T229	Phosphorylation	score1	PhosphoSitePlus
K249	Acetylation	score1	PhosphoSitePlus
T268	Phosphorylation	score1	PhosphoSitePlus
T276	Phosphorylation	score1	PhosphoSitePlus
S280	Phosphorylation	score1	PhosphoSitePlus
T301	Phosphorylation	score1	PhosphoSitePlus
K322	Acetylation	score1	PhosphoSitePlus
K328	Acetylation	score1	PhosphoSitePlus
K328	Ubiquitination	score1	PhosphoSitePlus
K348	Ubiquitination	score1	PhosphoSitePlus
K351	Acetylation	score1	PhosphoSitePlus
K351	Ubiquitination	score1	PhosphoSitePlus
K360	Acetylation	score1	PhosphoSitePlus
K360	Sumoylation	score1	PhosphoSitePlus
K360	Ubiquitination	score1	PhosphoSitePlus
K364	Sumoylation	score1	PhosphoSitePlus
K364	Ubiquitination	score1	PhosphoSitePlus
S365	Phosphorylation	score1	PhosphoSitePlus
T421	Phosphorylation	score1	PhosphoSitePlus
K454	Acetylation	score1	PhosphoSitePlus
K454	Ubiquitination	score1	PhosphoSitePlus
T465	Phosphorylation	score1	PhosphoSitePlus
R472	Methylation	score1	PhosphoSitePlus
T498	Phosphorylation	score1	PhosphoSitePlus
K500	Ubiquitination	score1	PhosphoSitePlus
K503	Ubiquitination	score1	PhosphoSitePlus
T505	O-Glycosylation	score1	GlyGen	16408927, 30397120, 18369606, ...34019948, 20305658, 36240223, 22121020
T505	Phosphorylation	score1	PhosphoSitePlus
K510	Acetylation	score1	PhosphoSitePlus
K510	Sumoylation	score1	PhosphoSitePlus
K510	Ubiquitination	score1	PhosphoSitePlus
K515	Acetylation	score1	PhosphoSitePlus
R520	Methylation	score1	PhosphoSitePlus
R527	Methylation	score1	PhosphoSitePlus
K564	Methylation	score1	PhosphoSitePlus
T634	Phosphorylation	score1	PhosphoSitePlus

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine By position T38 R50 T65 K101 T166 T178 S224 T229 T268 T301 T421 K454 R472	Variant Select all A229 A268 A421 C472 C50 F224 H472 I65 K178 M166 M178 M301 N454 R101 S38	Source Select all Biomuta	Disease [Sample source] Select all DOID:10534 / stomach cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] [ cosmic ]
T38	S38	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
R50	C50	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
T65	I65	Biomuta	[ cosmic ]
K101	R101	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
T166	M166	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ icgc ]
T178	K178	Biomuta	DOID:1781 / thyroid gland cancer [ cosmic ]
T178	M178	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S224	F224	Biomuta	DOID:10534 / stomach cancer [ cosmic, icgc ]
T229	A229	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
T268	A268	Biomuta	DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T301	M301	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
T421	A421	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
K454	N454	Biomuta	DOID:1324 / lung cancer [ cosmic ]
R472	C472	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
R472	H472	Biomuta	DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for P54652 (HSPA2)

Protein Information

Interactive Sequence View

P54652 (HSPA2) as Substrate

PTM sites affected in variants