iPTMnet Report for P54652 (HSPA2)
Protein Information
UniProt AC / UniProt ID | P54652 / HSP72_HUMAN |
Protein Name | Heat shock-related 70 kDa protein 2 |
Gene Name | Name: HSPA2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P54652 |
PRO Name | heat shock-related 70 kDa protein 2 (human) |
Definition | A heat shock-related 70 kDa protein 2 that is encoded in the genome of human. |
Short Label | hHSPA2 |
Category | organism-gene |
P54652 (HSPA2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y16 | Phosphorylation | score1 | PhosphoSitePlus | |||
K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
N36 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
T38 | Phosphorylation | score1 | PhosphoSitePlus | |||
T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
S41 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y42 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
T46 | Phosphorylation | score1 | PhosphoSitePlus | |||
T48 | Phosphorylation | score1 | PhosphoSitePlus | |||
R50 | Methylation | score1 | PhosphoSitePlus | |||
K57 | Acetylation | score1 | PhosphoSitePlus | |||
T65 | Phosphorylation | score1 | PhosphoSitePlus | |||
T67 | Phosphorylation | score1 | PhosphoSitePlus | |||
K72 | Acetylation | score1 | PhosphoSitePlus | |||
K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y108 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
K109 | Acetylation | score1 | PhosphoSitePlus | |||
K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
T112 | Phosphorylation | score1 | PhosphoSitePlus | |||
K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
S121 | Phosphorylation | score0 | HPRD | 20068231 | ||
S122 | Phosphorylation | score0 | HPRD | 20068231 | ||
T126 | Phosphorylation | score1 | PhosphoSitePlus | |||
T159 | Phosphorylation | score1 | PhosphoSitePlus | |||
T164 | Phosphorylation | score1 | PhosphoSitePlus | |||
T166 | Phosphorylation | score1 | PhosphoSitePlus | |||
T178 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y184 | Phosphorylation | score1 | PhosphoSitePlus | |||
K188 | Acetylation | score1 | PhosphoSitePlus | |||
K188 | Ubiquitination | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
T225 | Phosphorylation | score1 | PhosphoSitePlus | |||
T229 | Phosphorylation | score1 | PhosphoSitePlus | |||
K249 | Acetylation | score1 | PhosphoSitePlus | |||
T268 | Phosphorylation | score1 | PhosphoSitePlus | |||
T276 | Phosphorylation | score1 | PhosphoSitePlus | |||
S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
T301 | Phosphorylation | score1 | PhosphoSitePlus | |||
K322 | Acetylation | score1 | PhosphoSitePlus | |||
K328 | Acetylation | score1 | PhosphoSitePlus | |||
K328 | Ubiquitination | score1 | PhosphoSitePlus | |||
K348 | Ubiquitination | score1 | PhosphoSitePlus | |||
K351 | Acetylation | score1 | PhosphoSitePlus | |||
K351 | Ubiquitination | score1 | PhosphoSitePlus | |||
K360 | Acetylation | score1 | PhosphoSitePlus | |||
K360 | Sumoylation | score1 | PhosphoSitePlus | |||
K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
K364 | Sumoylation | score1 | PhosphoSitePlus | |||
K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
S365 | Phosphorylation | score1 | PhosphoSitePlus | |||
T421 | Phosphorylation | score1 | PhosphoSitePlus | |||
K454 | Acetylation | score1 | PhosphoSitePlus | |||
K454 | Ubiquitination | score1 | PhosphoSitePlus | |||
T465 | Phosphorylation | score1 | PhosphoSitePlus | |||
R472 | Methylation | score1 | PhosphoSitePlus | |||
T498 | Phosphorylation | score1 | PhosphoSitePlus | |||
K500 | Ubiquitination | score1 | PhosphoSitePlus | |||
K503 | Ubiquitination | score1 | PhosphoSitePlus | |||
T505 | O-Glycosylation | score1 | GlyGen | 16408927, 30397120, 18369606, ... | ||
T505 | Phosphorylation | score1 | PhosphoSitePlus | |||
K510 | Acetylation | score1 | PhosphoSitePlus | |||
K510 | Sumoylation | score1 | PhosphoSitePlus | |||
K510 | Ubiquitination | score1 | PhosphoSitePlus | |||
K515 | Acetylation | score1 | PhosphoSitePlus | |||
R520 | Methylation | score1 | PhosphoSitePlus | |||
R527 | Methylation | score1 | PhosphoSitePlus | |||
K564 | Methylation | score1 | PhosphoSitePlus | |||
T634 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T38 | S38 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
R50 | C50 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T65 | I65 | Biomuta | [ cosmic ] | |
K101 | R101 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T166 | M166 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ icgc ] | |
T178 | K178 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
T178 | M178 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S224 | F224 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T229 | A229 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T268 | A268 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
T301 | M301 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T421 | A421 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K454 | N454 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
R472 | C472 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R472 | H472 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] |