iPTMnet Report for P53804 (TTC3)
Protein Information
UniProt AC / UniProt ID | P53804 / TTC3_HUMAN |
Protein Name | E3 ubiquitin-protein ligase TTC3 |
Gene Name | Name: TTC3 Synonyms:DCRR1,RNF105,TPRD; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P53804 |
PRO Name | E3 ubiquitin-protein ligase TTC3 (human) |
Definition | An E3 ubiquitin-protein ligase TTC3 that is encoded in the genome of human. |
Short Label | hTTC3 |
Category | organism-gene |
P53804 (TTC3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
T221 | Phosphorylation | score1 | PhosphoSitePlus | |||
S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
K244 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y268 | Phosphorylation | score1 | PhosphoSitePlus | |||
K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
S310 | Phosphorylation | score1 | PhosphoSitePlus | |||
K337 | Ubiquitination | score1 | PhosphoSitePlus | |||
K345 | Ubiquitination | score1 | PhosphoSitePlus | |||
K348 | Ubiquitination | score1 | PhosphoSitePlus | |||
S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
S378 | Phosphorylation | P31749 (AKT1) | score3 | neXtProt PhosphoSitePlus Signor UniProt | 20059950 | |
K397 | Ubiquitination | score1 | PhosphoSitePlus | |||
S429 | Phosphorylation | score1 | PhosphoSitePlus | |||
K451 | Ubiquitination | score1 | PhosphoSitePlus | |||
T459 | Phosphorylation | score1 | PhosphoSitePlus | |||
K465 | Ubiquitination | score1 | PhosphoSitePlus | |||
K470 | Ubiquitination | score1 | PhosphoSitePlus | |||
K488 | Ubiquitination | score1 | PhosphoSitePlus | |||
K601 | Ubiquitination | score1 | PhosphoSitePlus | |||
K629 | Ubiquitination | score1 | PhosphoSitePlus | |||
K703 | Ubiquitination | score1 | PhosphoSitePlus | |||
K706 | Ubiquitination | score1 | PhosphoSitePlus | |||
K825 | Ubiquitination | score1 | PhosphoSitePlus | |||
S833 | Phosphorylation | score1 | IEDB | 35494241 | ||
T838 | Phosphorylation | score1 | IEDB | 35494241 | ||
C859 | Methylation | score1 | IEDB | 31844290 | ||
K902 | Ubiquitination | score1 | PhosphoSitePlus | |||
K948 | Ubiquitination | score1 | PhosphoSitePlus | |||
K955 | Ubiquitination | score1 | PhosphoSitePlus | |||
K967 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1006 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1009 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1018 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1097 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1135 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1153 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1189 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1190 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1196 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1204 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1244 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1278 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1288 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1517 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1519 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1530 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1581 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1584 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1596 | Acetylation | score1 | PhosphoSitePlus | |||
S1651 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1695 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1703 | Acetylation | score1 | PhosphoSitePlus | |||
K1705 | Acetylation | score1 | PhosphoSitePlus | |||
S1730 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1733 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1819 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1923 | Phosphorylation | score1 | phospho.ELM | 17081983 | ||
S1924 | Phosphorylation | score1 | phospho.ELM | 17081983 | ||
S1927 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1935 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
T1938 | Phosphorylation | score1 | phospho.ELM | 17081983 | ||
T2003 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K237 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S310 | C310 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K337 | N337 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K451 | T451 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K706 | E706 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K967 | N967 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K1018 | N1018 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S1244 | Y1244 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K1517 | R1517 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K1705 | E1705 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T1938 | I1938 | Biomuta | DOID:363 / uterine cancer [ icgc ] |