iPTMnet Report for P52952 (NKX2-5)
Protein Information
| UniProt AC / UniProt ID | P52952 / NKX25_HUMAN |
| Protein Name | Homeobox protein Nkx-2.5 |
| Gene Name | Name: NKX2-5 Synonyms:CSX,NKX2.5,NKX2E; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P52952 |
| PRO Name | homeobox protein Nkx-2.5 (human) |
| Definition | A homeobox protein Nkx-2.5 that is encoded in the genome of human. |
| Short Label | hNKX2-5 |
| Category | organism-gene |
DAG ViewP52952 (NKX2-5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S164 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T180 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R225 | Methylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S164 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 9858576 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T141 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T180 | M180 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R225 | S225 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
