iPTMnet Report for P51681 (CCR5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51681 / CCR5_HUMAN
Protein Name C-C chemokine receptor type 5
Gene Name Name: CCR5
Synonyms:CMKBR5;
Organism Homo sapiens (Human)

PRO ID PR:P51681
DAG View
PRO Name C-C chemokine receptor type 5 (human)
Definition A C-C chemokine receptor type 5 that is encoded in the genome of human.
Short Label hCCR5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51681 (CCR5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 O-Glycosylation GlyGen   UniProt 11733580
S7 O-Glycosylation GlyGen   UniProt 11733580
T195 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
S336 Phosphorylation L0R4T6 (ADRBK2) , P35626 (GRK3) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 12403770, 10085131
S337 Phosphorylation L0R4T6 (ADRBK2) , P35626 (GRK3) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 12403770, 10085131
Y339 Phosphorylation PhosphoSitePlus
S342 Phosphorylation P35626 (GRK3) , L0R4T6 (ADRBK2) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 10085131
T343 Phosphorylation PhosphoSitePlus
S349 Phosphorylation L0R4T6 (ADRBK2) , P35626 (GRK3) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 29283386, 21148810, 10085131


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T343 I343 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S349 F349 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S349 A349 Biomuta DOID:1324 / lung cancer [ cosmic ]