iPTMnet Report for P51681 (CCR5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51681 / CCR5_HUMAN
Protein Name C-C chemokine receptor type 5
Gene Name Name: CCR5
Synonyms:CMKBR5;
Organism Homo sapiens (Human)

PRO ID PR:P51681
DAG View
PRO Name C-C chemokine receptor type 5 (human)
Definition A C-C chemokine receptor type 5 that is encoded in the genome of human.
Short Label hCCR5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51681 (CCR5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 O-Glycosylation GlyGen   UniProt 11733580
S7 O-Glycosylation GlyGen   UniProt 11733580
T195 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
S336 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 12403770, 10085131
S336 Phosphorylation L0R4T6 (ADRBK2) HPRD 10085131
S336 Phosphorylation P35626 (GRK3) PhosphoSitePlus 10085131
S337 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 12403770, 10085131
S337 Phosphorylation L0R4T6 (ADRBK2) HPRD 10085131
S337 Phosphorylation P35626 (GRK3) PhosphoSitePlus 10085131
Y339 Phosphorylation PhosphoSitePlus
S342 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 10085131
S342 Phosphorylation L0R4T6 (ADRBK2) HPRD 10085131
S342 Phosphorylation P35626 (GRK3) PhosphoSitePlus 10085131
T343 Phosphorylation PhosphoSitePlus
S349 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 29283386, 21148810, 10085131
S349 Phosphorylation L0R4T6 (ADRBK2) HPRD 10085131
S349 Phosphorylation P35626 (GRK3) PhosphoSitePlus 10085131


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T343 I343 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S349 F349 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S349 A349 Biomuta DOID:1324 / lung cancer [ cosmic ]