Protein Information

Cytoscape View

UniProt AC / UniProt ID P51452 / DUS3_HUMAN
Protein Name Dual specificity protein phosphatase 3
Gene Name Name: DUSP3
Organism Homo sapiens (Human)

PRO ID PR:P51452
DAG View
PRO Name dual specificity protein phosphatase 3 (human)
Definition A dual specificity protein phosphatase 3 that is encoded in the genome of human.
Short Label hDUSP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P51452 (DUSP3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
Y38 Phosphorylation P43403 (ZAP70) , P43405 (SYK) neXtProt   PhosphoSitePlus 12447358
K50 Acetylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
T93 Phosphorylation PhosphoSitePlus
Y101 Phosphorylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
Y138 Phosphorylation P43403 (ZAP70) , P29597 (TYK2) , P43405 (SYK) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 12447358, 17785772
S149 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation HPRD 18491316
Y38 Phosphorylation HPRD 20068231
T133 Phosphorylation HPRD 20068231
Y138 Phosphorylation P43403 (ZAP70) HPRD 12447358

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T133 M133 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]