iPTMnet Report for P50549 (ETV1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50549 / ETV1_HUMAN
Protein Name ETS translocation variant 1
Gene Name Name: ETV1
Synonyms:ER81;
Organism Homo sapiens (Human)

PRO ID PR:P50549
DAG View
PRO Name ETS translocation variant 1 (human)
Definition An ETS translocation variant 1 that is encoded in the genome of human.
Short Label hETV1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50549 (ETV1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y5 Phosphorylation PhosphoSitePlus
K33 Acetylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus   RLIMS-P 22586091
S97 Phosphorylation PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
T139 Phosphorylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
S146 Phosphorylation IEDB   PhosphoSitePlus 27869121
S191 Phosphorylation Q15418 (RPS6KA1) , P17612 (PRKACA) , O75582 (RPS6KA5) , P49137 (MAPKAPK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12569367, 11551945, 10982847, ...12213813
S216 Phosphorylation P17612 (PRKACA) , P49137 (MAPKAPK2) , O75582 (RPS6KA5) , Q15418 (RPS6KA1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23774214, 10982847, 11551945, ...12213813, 12569367
C272 Methylation IEDB 31844290
S334 Phosphorylation Q15418 (RPS6KA1) , P17612 (PRKACA) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 25866208, 12213813
Y410 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K33 Acetylation PR:000007102 (EP300) PRO 12917345
K116 Acetylation PR:000007102 (EP300) PRO 12917345
T139 Phosphorylation HPRD 12917345
T143 Phosphorylation HPRD 12917345
S146 Phosphorylation HPRD 12917345
S191 Phosphorylation Q15418 (RPS6KA1) , P49137 (MAPKAPK2) , P17612 (PRKACA) , O75582 (RPS6KA5) HPRD 12569367, 11551945, 12917345, ...12213813
S216 Phosphorylation O75582 (RPS6KA5) , Q15418 (RPS6KA1) , P17612 (PRKACA) , P49137 (MAPKAPK2) HPRD 12569367, 11551945, 12917345, ...12213813
S334 Phosphorylation P17612 (PRKACA) , O75582 (RPS6KA5) , Q15418 (RPS6KA1) HPRD 12569367, 12213813


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000028573 (hETV1/iso:1/Ac:1) acK33,acK116 PR:000007102 (EP300) PRO 12917345


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K33 Q33 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K116 N116 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T143 M143 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S146 F146 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]