iPTMnet Report for P50549 (ETV1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50549 / ETV1_HUMAN
Protein Name ETS translocation variant 1
Gene Name Name: ETV1
Synonyms:ER81;
Organism Homo sapiens (Human)

PRO ID PR:P50549
DAG View
PRO Name ETS translocation variant 1 (human)
Definition An ETS translocation variant 1 that is encoded in the genome of human.
Short Label hETV1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50549 (ETV1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y5 Phosphorylation PhosphoSitePlus
K33 Acetylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus   RLIMS-P 22586091
S97 Phosphorylation PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
T139 Phosphorylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
S146 Phosphorylation IEDB   PhosphoSitePlus 27869121
S191 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12569367, 11551945, 10982847, ...12213813
S191 Phosphorylation O75582 (RPS6KA5) neXtProt 12569367
S191 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   Signor 12213813
S191 Phosphorylation P49137 (MAPKAPK2) neXtProt 11551945
S191 Phosphorylation Q15418 (RPS6KA1) neXtProt   Signor 12213813
S216 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23774214, 10982847, 11551945, ...12213813, 12569367
S216 Phosphorylation O75582 (RPS6KA5) neXtProt   Signor 12569367, 12213813
S216 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus 12213813
S216 Phosphorylation P49137 (MAPKAPK2) neXtProt 11551945
S216 Phosphorylation Q15418 (RPS6KA1) neXtProt   Signor 12213813
C272 Methylation IEDB 31844290
S334 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 25866208, 12213813
S334 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   Signor 12213813
S334 Phosphorylation Q15418 (RPS6KA1) neXtProt 12213813
Y410 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K33 Acetylation PRO 12917345
K33 Acetylation PR:000007102 (EP300) PRO 12917345
K116 Acetylation PRO 12917345
K116 Acetylation PR:000007102 (EP300) PRO 12917345
T139 Phosphorylation HPRD 12917345
T143 Phosphorylation HPRD 12917345
S146 Phosphorylation HPRD 12917345
S191 Phosphorylation HPRD 12569367, 11551945, 12917345, ...12213813
S191 Phosphorylation O75582 (RPS6KA5) HPRD 12569367
S191 Phosphorylation P17612 (PRKACA) HPRD 12569367, 11551945, 12917345, ...12213813
S191 Phosphorylation P49137 (MAPKAPK2) HPRD 11551945
S191 Phosphorylation Q15418 (RPS6KA1) HPRD 12569367, 11551945, 12917345, ...12213813
S216 Phosphorylation HPRD 12569367, 11551945, 12917345, ...12213813
S216 Phosphorylation O75582 (RPS6KA5) HPRD 12569367
S216 Phosphorylation P17612 (PRKACA) HPRD 12569367, 11551945, 12917345, ...12213813
S216 Phosphorylation P49137 (MAPKAPK2) HPRD 11551945
S216 Phosphorylation Q15418 (RPS6KA1) HPRD 12569367, 11551945, 12917345, ...12213813
S334 Phosphorylation HPRD 12569367, 12213813
S334 Phosphorylation O75582 (RPS6KA5) HPRD 12569367
S334 Phosphorylation P17612 (PRKACA) HPRD 12569367, 12213813
S334 Phosphorylation Q15418 (RPS6KA1) HPRD 12569367, 12213813


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000028573 (hETV1/iso:1/Ac:1) acK33,acK116 PR:000007102 (EP300) PRO 12917345


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K33 Q33 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K116 N116 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T143 M143 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S146 F146 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]