iPTMnet Report for P50542 (PEX5)
Protein Information
| UniProt AC / UniProt ID | P50542 / PEX5_HUMAN |
| Protein Name | Peroxisomal targeting signal 1 receptor |
| Gene Name | Name: PEX5 Synonyms:PXR1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P50542 |
| PRO Name | peroxisomal targeting signal 1 receptor (human) |
| Definition | A peroxisomal targeting signal 1 receptor that is encoded in the genome of human. |
| Short Label | hPEX5 |
| Category | organism-gene |
DAG ViewP50542 (PEX5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K28 | Acetylation | score1 | PhosphoSitePlus | |||
| K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S58 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K83 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S115 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S141 | Phosphorylation | Q13315 (ATM) | score4 | PhosphoSitePlus RLIMS-P Signor UniProt | 26344566, 27050462 | |
| T149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S153 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S155 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| Y163 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S167 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| Y185 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y188 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K209 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 26344566 | ||
| K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S228 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K278 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S279 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| S283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y312 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S317 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K322 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K456 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K472 | Ubiquitination | score2 | UniProt | 28724525 | ||
| K527 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 24662292 | ||
| T633 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K209 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S279 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K464 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K519 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T622 | Phosphorylation | score0 | HPRD | 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S57 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K52 | E52 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| K83 | N83 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y185 | F185 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K204 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S228 | F228 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K290 | T290 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| Y312 | N312 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K322 | T322 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T622 | I622 | Biomuta | [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ] |
