Protein Information

Cytoscape View


UniProt AC / UniProt ID P49419 / AL7A1_HUMAN
Protein Name Alpha-aminoadipic semialdehyde dehydrogenase precursor
Gene Name Name: ALDH7A1
Synonyms:ATQ1;
Organism Homo sapiens (Human)

PRO ID PR:P49419
DAG View
PRO Name alpha-aminoadipic semialdehyde dehydrogenase (human)
Definition An alpha-aminoadipic semialdehyde dehydrogenase that is encoded in the genome of human.
Short Label hALDH7A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49419 (ALDH7A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y39 Phosphorylation PhosphoSitePlus
Y69 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
Y88 Phosphorylation PhosphoSitePlus
K93 Acetylation PhosphoSitePlus
K94 Acetylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
K389 Acetylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K439 Acetylation PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
C522 S-Nitrosylation dbSNO 26338901
K528 Acetylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S130 Phosphorylation HPRD 20068231
S133 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K109 T109 Biomuta DOID:1324 / lung cancer [ cosmic ]
K109 Q109 Biomuta DOID:1324 / lung cancer [ cosmic ]
S171 F171 Biomuta DOID:363 / uterine cancer [ tcga ]
K439 Q439 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K452 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]