iPTMnet Report for P43146 (DCC)
Protein Information
UniProt AC / UniProt ID | P43146 / DCC_HUMAN |
Protein Name | Netrin receptor DCC precursor |
Gene Name | Name: DCC Synonyms:IGDCC1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P43146 |
PRO Name | netrin receptor DCC (human) |
Definition | A netrin receptor DCC that is encoded in the genome of human. |
Short Label | hDCC |
Category | organism-gene |
P43146 (DCC) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y115 | Phosphorylation | score1 | PhosphoSitePlus | |||
S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
T156 | Phosphorylation | score1 | PhosphoSitePlus | |||
T479 | Phosphorylation | score1 | PhosphoSitePlus | |||
T488 | Phosphorylation | score1 | PhosphoSitePlus | |||
T521 | Phosphorylation | score1 | PhosphoSitePlus | |||
S642 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y809 | Phosphorylation | score1 | PhosphoSitePlus | |||
S811 | Phosphorylation | score1 | PhosphoSitePlus | |||
T813 | Phosphorylation | score1 | PhosphoSitePlus | |||
T814 | Phosphorylation | score1 | PhosphoSitePlus | |||
S868 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y881 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1073 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1074 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1142 | Acetylation | score1 | PhosphoSitePlus | |||
Y1363 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1420 | Phosphorylation | P06241 (FYN) | score3 | neXtProt PRO PhosphoSitePlus | 15557120 |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000047140 (hDCC/SigPep-/Phos:1) | pY1420 | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S129 | R129 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S129 | T129 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
T156 | K156 | Biomuta | DOID:1324 / lung cancer [ icgc ] | |
T156 | R156 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T479 | K479 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T488 | P488 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S642 | R642 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S642 | I642 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T813 | P813 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
T814 | I814 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S868 | F868 | Biomuta | [ cosmic ] | |
S868 | P868 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
Y881 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y881 | C881 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T1074 | I1074 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |