iPTMnet Report for P43146 (DCC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P43146 / DCC_HUMAN
Protein Name Netrin receptor DCC precursor
Gene Name Name: DCC
Synonyms:IGDCC1;
Organism Homo sapiens (Human)

PRO ID PR:P43146
DAG View
PRO Name netrin receptor DCC (human)
Definition A netrin receptor DCC that is encoded in the genome of human.
Short Label hDCC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P43146 (DCC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y115 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
T156 Phosphorylation PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus
T488 Phosphorylation PhosphoSitePlus
T521 Phosphorylation PhosphoSitePlus
S642 Phosphorylation PhosphoSitePlus
Y809 Phosphorylation PhosphoSitePlus
S811 Phosphorylation PhosphoSitePlus
T813 Phosphorylation PhosphoSitePlus
T814 Phosphorylation PhosphoSitePlus
S868 Phosphorylation PhosphoSitePlus
Y881 Phosphorylation PhosphoSitePlus
S1073 Phosphorylation PhosphoSitePlus
T1074 Phosphorylation PhosphoSitePlus
K1142 Acetylation PhosphoSitePlus
Y1363 Phosphorylation PhosphoSitePlus
Y1420 Phosphorylation neXtProt   PRO   PhosphoSitePlus 15557120
Y1420 Phosphorylation P06241 (FYN) neXtProt 15557120


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047140 (hDCC/SigPep-/Phos:1) pY1420 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S129 R129 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S129 T129 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T156 K156 Biomuta DOID:1324 / lung cancer [ icgc ]
T156 R156 Biomuta DOID:3571 / liver cancer [ cosmic ]
T479 K479 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T488 P488 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S642 R642 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S642 I642 Biomuta DOID:1324 / lung cancer [ cosmic ]
T813 P813 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T814 I814 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S868 F868 Biomuta [ cosmic ]
S868 P868 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y881 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y881 C881 Biomuta DOID:363 / uterine cancer [ icgc ]
T1074 I1074 Biomuta DOID:4159 / skin cancer [ cosmic ]