iPTMnet Report for P42357 (HAL)
Protein Information
| UniProt AC / UniProt ID | P42357 / HUTH_HUMAN |
| Protein Name | Histidine ammonia-lyase |
| Gene Name | Name: HAL Synonyms:HIS; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P42357 |
| PRO Name | histidine ammonia-lyase (human) |
| Definition | A histidine ammonia-lyase that is encoded in the genome of human. |
| Short Label | hHAL |
| Category | organism-gene |
DAG ViewP42357 (HAL) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K59 | Acetylation | score1 | PhosphoSitePlus | |||
| K158 | Acetylation | score1 | PhosphoSitePlus | |||
| K160 | Acetylation | score1 | PhosphoSitePlus | |||
| Y222 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S226 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K298 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T337 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T410 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T419 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T420 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S635 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y222 | C222 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| S226 | Y226 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S226 | F226 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] |
