iPTMnet Report for P42357 (HAL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P42357 / HUTH_HUMAN
Protein Name Histidine ammonia-lyase
Gene Name Name: HAL
Synonyms:HIS;
Organism Homo sapiens (Human)

PRO ID PR:P42357
DAG View
PRO Name histidine ammonia-lyase (human)
Definition A histidine ammonia-lyase that is encoded in the genome of human.
Short Label hHAL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P42357 (HAL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K59 Acetylation PhosphoSitePlus
K158 Acetylation PhosphoSitePlus
K160 Acetylation PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
T337 Phosphorylation PhosphoSitePlus
T410 Phosphorylation PhosphoSitePlus
T419 Phosphorylation PhosphoSitePlus
T420 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y222 C222 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S226 Y226 Biomuta DOID:363 / uterine cancer [ icgc ]
S226 F226 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]