iPTMnet Report for P41970 (ELK3)
Protein Information
| UniProt AC / UniProt ID | P41970 / ELK3_HUMAN |
| Protein Name | ETS domain-containing protein Elk-3 |
| Gene Name | Name: ELK3 Synonyms:NET,SAP2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P41970 |
| PRO Name | ETS domain-containing protein Elk-3 (human) |
| Definition | An ETS domain-containing protein Elk-3 that is encoded in the genome of human. |
| Short Label | hELK3 |
| Category | organism-gene |
P41970 (ELK3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K83 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S115 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976 | ||
| S145 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S150 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K162 | Sumoylation | score1 | PhosphoSitePlus | |||
| S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K189 | Acetylation | score1 | PhosphoSitePlus | |||
| T195 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| S200 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| S203 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| T204 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| S205 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| S211 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| S245 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 15302935 | ||
| S247 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S270 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S286 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S357 | Phosphorylation | score4 | HPRD neXtProt phospho.ELM Signor | 9130707, 11042694 | ||
| S357 | Phosphorylation | P45983 (MAPK8) | score3 | HPRD neXtProt | 11042694 | |
| S357 | Phosphorylation | P45984 (MAPK9) | score3 | HPRD neXtProt | 11042694 | |
| S357 | Phosphorylation | Q16539 (MAPK14) | score1 | Signor | 9130707 | |
| S363 | Phosphorylation | score4 | HPRD neXtProt phospho.ELM Signor | 9130707, 11042694 | ||
| S363 | Phosphorylation | P45983 (MAPK8) | score2 | neXtProt | 11042694 | |
| S363 | Phosphorylation | P45984 (MAPK9) | score2 | neXtProt | 11042694 | |
| S363 | Phosphorylation | Q16539 (MAPK14) | score3 | HPRD Signor | 9130707, 11042694 | |
| S396 | Phosphorylation | score4 | HPRD neXtProt PhosphoSitePlus UniProt | 23186163, 19007248, 11042694 | ||
| S396 | Phosphorylation | P45983 (MAPK8) | score2 | neXtProt | 11042694 | |
| S396 | Phosphorylation | P45984 (MAPK9) | score2 | neXtProt | 11042694 | |
| S401 | Phosphorylation | score2 | neXtProt | 11042694 | ||
| S401 | Phosphorylation | P45983 (MAPK8) | score2 | neXtProt | 11042694 | |
| S401 | Phosphorylation | P45984 (MAPK9) | score2 | neXtProt | 11042694 | |
| S404 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S407 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S145 | A145 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S145 | P145 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S200 | P200 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T204 | M204 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S211 | Y211 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S401 | F401 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View