Protein Information

Cytoscape View

UniProt AC / UniProt ID P41970 / ELK3_HUMAN
Protein Name ETS domain-containing protein Elk-3
Gene Name Name: ELK3
Organism Homo sapiens (Human)

PRO ID PR:P41970
DAG View
PRO Name ETS domain-containing protein Elk-3 (human)
Definition An ETS domain-containing protein Elk-3 that is encoded in the genome of human.
Short Label hELK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P41970 (ELK3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K58 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
S115 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976
S145 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
K162 Sumoylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K189 Acetylation PhosphoSitePlus
S245 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15302935
S247 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
S357 Phosphorylation Q16539 (MAPK14) , P45983 (MAPK8) , P45984 (MAPK9) HPRD   neXtProt   phospho.ELM   Signor 9130707, 11042694
S363 Phosphorylation P45984 (MAPK9) , P45983 (MAPK8) , Q16539 (MAPK14) HPRD   neXtProt   phospho.ELM   Signor 9130707, 11042694
S396 Phosphorylation P45984 (MAPK9) , P45983 (MAPK8) HPRD   neXtProt   PhosphoSitePlus   UniProt 23186163, 19007248, 11042694
S401 Phosphorylation P45983 (MAPK8) , P45984 (MAPK9) neXtProt 11042694
S404 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K113 N113 Biomuta DOID:3571 / liver cancer [ icgc ]
S145 P145 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S363 I363 Biomuta DOID:3571 / liver cancer [ icgc ]