iPTMnet Report for P40259 (CD79B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40259 / CD79B_HUMAN
Protein Name B-cell antigen receptor complex-associated protein beta chain precursor
Gene Name Name: CD79B
Synonyms:B29,IGB;
Organism Homo sapiens (Human)

PRO ID PR:P40259
DAG View
PRO Name B-cell antigen receptor complex-associated protein beta chain (human)
Definition A B-cell antigen receptor complex-associated protein beta chain that is encoded in the genome of human.
Short Label hCD79B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40259 (CD79B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N68 N-Glycosylation GlyGen 24190977
N73 N-Glycosylation GlyGen 24190977
S99 Phosphorylation PhosphoSitePlus
N101 N-Glycosylation GlyGen 24190977
N127 N-Glycosylation GlyGen 24190977
N128 N-Glycosylation GlyGen 24190977
C136 Methylation IEDB 31844290
S146 Phosphorylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
T195 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 24769851, 9531288, 7592958
Y196 Phosphorylation P06241 (FYN) phospho.ELM 9531288
Y196 Phosphorylation P07948 (LYN) phospho.ELM 9531288
Y196 Phosphorylation P51451 (BLK) neXtProt 7592958
Y207 Phosphorylation neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 24769851, 9531288, 7592958
Y207 Phosphorylation P06241 (FYN) phospho.ELM 9531288
Y207 Phosphorylation P07948 (LYN) phospho.ELM 9531288
Y207 Phosphorylation P51451 (BLK) neXtProt 7592958
K219 Acetylation IEDB 34357683
K219 Ubiquitination PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y196 Phosphorylation HPRD 9531288, 8077654
Y196 Phosphorylation P06239 (LCK) HPRD 8077654
Y196 Phosphorylation P06241 (FYN) HPRD 9531288
Y196 Phosphorylation P07948 (LYN) HPRD 9531288
Y207 Phosphorylation HPRD 9531288, 8077654
Y207 Phosphorylation P06239 (LCK) HPRD 8077654
Y207 Phosphorylation P06241 (FYN) HPRD 9531288
Y207 Phosphorylation P07948 (LYN) HPRD 9531288
Site PTM Type PTM Enzyme Score Source PMID
Y92 Phosphorylation HPRD 9531288, 8077654
Y92 Phosphorylation P06239 (LCK) HPRD 8077654
Y92 Phosphorylation P06241 (FYN) HPRD 9531288
Y92 Phosphorylation P07948 (LYN) HPRD 9531288
Y103 Phosphorylation HPRD 9531288, 8077654
Y103 Phosphorylation P06239 (LCK) HPRD 8077654
Y103 Phosphorylation P06241 (FYN) HPRD 9531288
Y103 Phosphorylation P07948 (LYN) HPRD 9531288
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046649 (hCD79B/SigPep-/Phos:1) pY196,pY207 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N68 Y68 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
N73 T73 Biomuta DOID:2394 / ovarian cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
Y92 H92 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y92 C92 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y92 D92 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y92 F92 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y92 R92 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y92 S92 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y92 N92 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y92 * Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S99 F99 Biomuta [ cosmic ]
N101 Y101 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y103 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y103 H103 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y103 N103 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
N127 S127 Biomuta DOID:1324 / lung cancer [ cosmic ]
N128 S128 Biomuta DOID:4159 / skin cancer [ cosmic ]
T195 S195 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y196 * Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
Y196 R196 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y196 S196 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y196 N196 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y196 H196 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y196 D196 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y196 F196 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc, tcga ]
Y196 C196 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y207 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y207 H207 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y207 N207 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S221 F221 Biomuta [ cosmic ]