iPTMnet Report for P40259 (CD79B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40259 / CD79B_HUMAN
Protein Name B-cell antigen receptor complex-associated protein beta chain precursor
Gene Name Name: CD79B
Synonyms:B29,IGB;
Organism Homo sapiens (Human)

PRO ID PR:P40259
DAG View
PRO Name B-cell antigen receptor complex-associated protein beta chain (human)
Definition A B-cell antigen receptor complex-associated protein beta chain that is encoded in the genome of human.
Short Label hCD79B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40259 (CD79B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N68 N-Glycosylation GlyGen 24190977
N73 N-Glycosylation GlyGen 24190977
S99 Phosphorylation PhosphoSitePlus
N101 N-Glycosylation GlyGen 24190977
N127 N-Glycosylation GlyGen 24190977
N128 N-Glycosylation GlyGen 24190977
C136 Methylation IEDB 31844290
S146 Phosphorylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
T195 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation P06241 (FYN) , P51451 (BLK) , P07948 (LYN) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 24769851, 9531288, 7592958
Y207 Phosphorylation P51451 (BLK) , P07948 (LYN) , P06241 (FYN) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 24769851, 9531288, 7592958
K219 Acetylation IEDB 34357683
K219 Ubiquitination PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y196 Phosphorylation P06239 (LCK) , P07948 (LYN) , P06241 (FYN) HPRD 9531288, 8077654
Y207 Phosphorylation P07948 (LYN) , P06241 (FYN) , P06239 (LCK) HPRD 9531288, 8077654
Site PTM Type PTM Enzyme Score Source PMID
Y92 Phosphorylation P06239 (LCK) , P06241 (FYN) , P07948 (LYN) HPRD 9531288, 8077654
Y103 Phosphorylation P07948 (LYN) , P06239 (LCK) , P06241 (FYN) HPRD 9531288, 8077654
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046649 (hCD79B/SigPep-/Phos:1) pY196,pY207 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N68 Y68 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
N73 T73 Biomuta DOID:2394 / ovarian cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
Y92 H92 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y92 C92 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y92 D92 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y92 F92 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y92 R92 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y92 S92 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y92 N92 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y92 * Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S99 F99 Biomuta [ cosmic ]
N101 Y101 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y103 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y103 H103 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y103 N103 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
N127 S127 Biomuta DOID:1324 / lung cancer [ cosmic ]
N128 S128 Biomuta DOID:4159 / skin cancer [ cosmic ]
T195 S195 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y196 * Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
Y196 R196 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y196 S196 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y196 N196 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y196 H196 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y196 D196 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y196 F196 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc, tcga ]
Y196 C196 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
Y207 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y207 H207 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y207 N207 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S221 F221 Biomuta [ cosmic ]