Protein Information

Cytoscape View


UniProt AC / UniProt ID P40259 / CD79B_HUMAN
Protein Name B-cell antigen receptor complex-associated protein beta chain precursor
Gene Name Name: CD79B
Synonyms:B29,IGB;
Organism Homo sapiens (Human)

PRO ID PR:P40259
DAG View
PRO Name B-cell antigen receptor complex-associated protein beta chain (human)
Definition A B-cell antigen receptor complex-associated protein beta chain that is encoded in the genome of human.
Short Label hCD79B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40259 (CD79B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S99 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
T195 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation P06241 (FYN) , P51451 (BLK) , P07948 (LYN) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 24769851, 9531288, 7592958
Y207 Phosphorylation P51451 (BLK) , P07948 (LYN) , P06241 (FYN) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 24769851, 9531288, 7592958
K219 Ubiquitination PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y196 Phosphorylation P06239 (LCK) , P07948 (LYN) , P06241 (FYN) HPRD 9531288, 8077654
Y207 Phosphorylation P07948 (LYN) , P06241 (FYN) , P06239 (LCK) HPRD 9531288, 8077654
Site PTM Type PTM Enzyme Score Source PMID
Y92 Phosphorylation P07948 (LYN) , P06239 (LCK) , P06241 (FYN) HPRD 9531288, 8077654
Y103 Phosphorylation P07948 (LYN) , P06239 (LCK) , P06241 (FYN) HPRD 9531288, 8077654
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046649 (hCD79B/SigPep-/Phos:1) pY196,pY207 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S99 Y99 Biomuta DOID:3571 / liver cancer [ icgc ]
Y196 S196 Biomuta DOID:2531 / hematologic cancer [ icgc ]
Y196 N196 Biomuta DOID:2531 / hematologic cancer [ icgc, tcga ]
Y196 H196 Biomuta DOID:2531 / hematologic cancer [ icgc, tcga ]
Y196 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y196 F196 Biomuta DOID:2531 / hematologic cancer [ tcga ]
Y196 C196 Biomuta DOID:2531 / hematologic cancer [ icgc, tcga ]