iPTMnet Report for P39905 (GDNF)
Protein Information
| UniProt AC / UniProt ID | P39905 / GDNF_HUMAN |
| Protein Name | Glial cell line-derived neurotrophic factor precursor |
| Gene Name | Name: GDNF |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P39905 |
| PRO Name | glial cell line-derived neurotrophic factor (human) |
| Definition | A glial cell line-derived neurotrophic factor that is encoded in the genome of human. |
| Short Label | hGDNF |
| Category | organism-gene |
DAG ViewP39905 (GDNF) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N126 | N-Glycosylation | score3 | GlyGen UniProt | 19478429 | ||
| S146 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T155 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y156 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S164 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T154 | I154 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T155 | M155 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| Y156 | H156 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S164 | F164 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S164 | C164 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
