Protein Information

Cytoscape View

UniProt AC / UniProt ID P39905 / GDNF_HUMAN
Protein Name Glial cell line-derived neurotrophic factor precursor
Gene Name Name: GDNF
Organism Homo sapiens (Human)

PRO ID PR:P39905
DAG View
PRO Name glial cell line-derived neurotrophic factor (human)
Definition A glial cell line-derived neurotrophic factor that is encoded in the genome of human.
Short Label hGDNF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P39905 (GDNF) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N126 N-Glycosylation UniProt 19478429
S146 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
T155 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T154 I154 Biomuta DOID:1324 / lung cancer [ tcga ]
T155 M155 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:3963 / thyroid carcinoma [ tcga ] DOID:1324 / lung cancer [ cosmic ]
Y156 H156 Biomuta DOID:1909 / melanoma [ cosmic ]
Y156 N156 Biomuta DOID:1612 / breast cancer [ tcga ]
S164 F164 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S164 C164 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]