iPTMnet Report for P36871 (PGM1)
Protein Information
| UniProt AC / UniProt ID | P36871 / PGM1_HUMAN |
| Protein Name | Phosphoglucomutase-1 |
| Gene Name | Name: PGM1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P36871 |
| PRO Name | phosphoglucomutase-1 (human) |
| Definition | A phosphoglucomutase-1 that is encoded in the genome of human. |
| Short Label | hPGM1 |
| Category | organism-gene |
P36871 (PGM1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 21406692, 22814378 | ||
| K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y12 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K16 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K16 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y66 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T115 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S117 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 18669648, 25288802, ... | ||
| S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K172 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T185 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| Y195 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T197 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S201 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S206 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| K219 | Acetylation | score1 | PhosphoSitePlus | |||
| Y232 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S247 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R293 | Methylation | score1 | PhosphoSitePlus | |||
| S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R343 | Methylation | score1 | PhosphoSitePlus | |||
| S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T348 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y353 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T355 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T357 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S369 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S378 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S408 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K419 | Acetylation | score1 | PhosphoSitePlus | |||
| K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y430 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R452 | Methylation | score1 | PhosphoSitePlus | |||
| K457 | Acetylation | score1 | PhosphoSitePlus | |||
| K457 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T467 | Phosphorylation | score3 | neXtProt phospho.ELM PhosphoSitePlus Signor UniProt | 15378030 | ||
| T467 | Phosphorylation | Q13153 (PAK1) | score3 | neXtProt phospho.ELM PhosphoSitePlus Signor | 15378030 | |
| T467 | Phosphorylation | Q16512 (PKN1) | score1 | Signor | 15378030 | |
| K470 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y476 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R491 | Methylation | score1 | PhosphoSitePlus | |||
| T495 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S505 | O-Glycosylation | score1 | GlyGen | 16408927, 26374642, 34725712, ... | ||
| S505 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T507 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S509 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T513 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y521 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S541 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T19 | Phosphorylation | score0 | HPRD | 20166139 | ||
| T115 | Phosphorylation | score0 | HPRD | 18212344, 20058876, 19651622, ... | ||
| S117 | Phosphorylation | score0 | HPRD | 17081983, 18767875, 20058876, ... | ||
| Y353 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S369 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S505 | Phosphorylation | score0 | HPRD | 20166139 | ||
| T507 | Phosphorylation | score0 | HPRD | 20166139 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T133 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S135 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K146 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K146 | T146 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S201 | I201 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S206 | I206 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S247 | L247 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
| R343 | W343 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
| K349 | T349 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T355 | A355 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| R452 | C452 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| R491 | H491 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| R491 | C491 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y521 | F521 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S541 | F541 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View